Gender Differences in Clinical Features
and In-hospital Outcomes in ST-segment
Elevation Acute Myocardial Infarction:
From the Korean Acute Myocardial
Infarction Registry (KAMIR) Study
- Affiliated Author(s)
- Alternative Author(s)
- Hur, Seung Ho
- Journal Title
- Clinical Cardiology
- Issued Date
- Background: Studies have suggested that women are biologically different and that female gender itself is
independently associated with poor clinical outcome after an acute myocardial infarction (AMI).
Hypothesis: We analyzed data from the Korean Acute Myocardial InfarctionRegistry (KAMIR) to assess gender
differences in in-hospital outcomes post ST-segment elevation myocardial infarction (STEMI).
Methods: Between November 2005 and July 2007, 4037 patientswho were admitted with STEMI to 41 facilities
were registered into the KAMIR database; patients admitted within 72 hours of symptom onset were selected
Results: The proportion of patients who had reperfusion therapy within 12 hours from chest pain onset was
lower in women. Women had higher rates of in-hospital mortality (8.6% vs 3.2%, P <.01), noncardiac death
(1.5% vs 0.4%, P <.01), cardiac death (7.1% vs 2.8%, P <.01), and stroke (1.2% vs 0.5%, P <.05) than men.
Multivariate logistic regression analysis identified age, previous angina, hypertension, a Killip class ≥ II, a
left ventricular ejection fraction (LVEF) <40%, and a thrombolysis in myocardial infarction flow (TIMI) grade
≤3 after angioplasty as independent risk factors for in-hospitaldeath for all patients; however, female gender
itself was not an independent risk factor.
Conclusions: The results of this study show that although women have a higher in-hospital mortality than
men, female gender itself is not an independent risk factor for in-hospital mortality.
- Authorize & License
- Files in This Item:
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.