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Gender Differences in Clinical Features and In-hospital Outcomes in ST-segment Elevation Acute Myocardial Infarction: From the Korean Acute Myocardial Infarction Registry (KAMIR) Study

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Author(s)
Jong-Seon ParkYoung-Jo KimDong-Gu ShinMyung-Ho JeongYoung-Keun AhnWook-Sung ChungKi-Bae SeungChong-Jin KimMyeong-Chan ChoYang-Soo JangSeung-Jung ParkIn-Whan SeongShung-Chull ChaeSeung-Ho HurDong-Hoon ChoiTaek-Jong Hong
Keimyung Author(s)
Hur, Seung Ho
Department
Dept. of Internal Medicine (내과학)
Journal Title
Clinical Cardiology
Issued Date
2010
Volume
33
Issue
8
Abstract
Background: Studies have suggested that women are biologically different and that female gender itself is
independently associated with poor clinical outcome after an acute myocardial infarction (AMI).
Hypothesis: We analyzed data from the Korean Acute Myocardial InfarctionRegistry (KAMIR) to assess gender
differences in in-hospital outcomes post ST-segment elevation myocardial infarction (STEMI).
Methods: Between November 2005 and July 2007, 4037 patientswho were admitted with STEMI to 41 facilities
were registered into the KAMIR database; patients admitted within 72 hours of symptom onset were selected
andincludedinthisstudy.
Results: The proportion of patients who had reperfusion therapy within 12 hours from chest pain onset was
lower in women. Women had higher rates of in-hospital mortality (8.6% vs 3.2%, P <.01), noncardiac death
(1.5% vs 0.4%, P <.01), cardiac death (7.1% vs 2.8%, P <.01), and stroke (1.2% vs 0.5%, P <.05) than men.
Multivariate logistic regression analysis identified age, previous angina, hypertension, a Killip class ≥ II, a
left ventricular ejection fraction (LVEF) <40%, and a thrombolysis in myocardial infarction flow (TIMI) grade
≤3 after angioplasty as independent risk factors for in-hospitaldeath for all patients; however, female gender
itself was not an independent risk factor.
Conclusions: The results of this study show that although women have a higher in-hospital mortality than
men, female gender itself is not an independent risk factor for in-hospital mortality.
Keimyung Author(s)(Kor)
허승호
Publisher
School of Medicine
Citation
Jong-Seon Park et al. (2010). Gender Differences in Clinical Features
and In-hospital Outcomes in ST-segment
Elevation Acute Myocardial Infarction:
From the Korean Acute Myocardial
Infarction Registry (KAMIR) Study. Clinical Cardiology, 33(8), E1–E6. doi: 10.1002/clc.20557
Type
Article
ISSN
0160-9289
DOI
10.1002/clc.20557
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/35484
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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