Peritoneal Carcinomatosis in Patients With Ovarian Cancer
Enhanced CT Versus 18F-FDG PET/CT
- Affiliated Author(s)
- 김해원; 원경숙; 전석길
- Alternative Author(s)
- Kim, Hae Won; Won, Kyoung Sook; Zeon, Seok Kil
- Journal Title
- Clinical Nuclear Medicine
- Issued Date
- Purpose: The study aimed to evaluate the efficacy of PET/CT in detecting
peritoneal carcinomatosis in patients with ovarian cancer and to compare the
diagnostic accuracy of FDG PET/CT with that of enhanced abdominal CT.
Methods: The medical records of 46 consecutive patients with ovarian cancer
were reviewed, and the presence of peritoneal tumor on 18F-FDG PET/CT and
enhanced abdominal CT scans was also assessed. Imaging results were compared
with the pathologic findings obtained by surgery.
Results: Pathologic results were positive for peritoneal carcinomatosis in 26
patients and negative in 20 patients. PET/CT correctly detected 25 of 26 patients
with peritoneal carcinomatosis and enhanced abdominal CT correctly detected
23 of 26 patients. Sensitivity and specificity for the diagnosis of peritoneal
carcinomatosis were 96.2% and 90%, respectively, for PET/CT and 88.5% and
65%, respectively, for enhanced abdominal CT. The accuracy of PET/CT
was statistically higher than that of enhanced abdominal CT (93.5% vs 78.3%,
P = 0.039). Four distinctly abnormal PET/CT findings of single nodular,
multiple nodular, diffuse, and mixed FDG uptakes were identified and corresponded
to pathologic findings.
Conclusions: 18F-FDG PET/CT imaging is efficient in the diagnosis of
peritoneal carcinomatosis and its performance is superior to that of enhanced
KeyWords: ovarian cancer, peritoneal carcinomatosis, PET/CT, enhanced CT,
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