계명대학교 의학도서관 Repository

Morphologic Changes in Trabecular Meshwork after Patterned and Argon Laser Trabeculoplasty in Cats

Metadata Downloads
Author(s)
Jong Yeon LeeSeung Yeon HaHae Jung PaikKun-Young KwonYong Yeon Kim
Keimyung Author(s)
Kwon, Kun Young
Department
Dept. of Pathology (병리학)
Journal Title
Current Eye Research
Issued Date
2014
Volume
39
Issue
9
Abstract
Purpose: Patterned laser trabeculoplasty (PLT) was introduced as it claimed to cause less thermal damage and provide more uniform coverage of the trabecular meshwork than argon laser trabeculoplasty (ALT). The objective of this study was to investigate morphologic changes in the trabecular meshwork after PLT or ALT in cats. Materials and Methods: We performed ALT in the right eyes and PLT in the left eyes of 6 domestic cats. A seventh cat was assigned as a control. Two ranges of laser energy were used for PLT: supra-threshold energy of 400-450 mW in 3 cats and sub-threshold energy of 250 to 350 mW in 3 cats. Specimens were obtained at 1, 4 and 9 weeks after treatment. Structural changes in the trabecular meshwork were evaluated by light microscopy and scanning electron microscopy. Results: The trabecular meshwork after supra-threshold PLT revealed coagulative damage such as a crater-like lesion with disruption of trabecular beams in early period and extensive membranous obliteration in the late period (at 4 and 9 weeks after treatment), which were comparable to tissue changes after ALT. Sub-threshold PLT resulted in thinning of the uveal meshwork and denudation of trabecular endothelial cells whereas it did not disrupt trabecular beams. Nevertheless, following sub-threshold PLT, partial membranous coverages were observed in the trabecular meshwork in the late period. Conclusions: When used at sub-threshold power, PLT caused less thermal damage to the trabecular meshwork than ALT. However, it did not effectively prevent late scarring of the trabecular meshwork in cats. [ FROM AUTHOR] .
Keimyung Author(s)(Kor)
권건영
Publisher
School of Medicine
Citation
Jong Yeon Lee et al. (2014). Morphologic Changes in Trabecular Meshwork after Patterned and Argon Laser Trabeculoplasty in Cats. Current Eye Research, 39(9), 908–916. doi: 10.3109/02713683.2014.884596
Type
Article
ISSN
0271-3683
Source
http://lps3.www.tandfonline.com.proxy.dsmc.or.kr/doi/abs/10.3109/02713683.2014.884596?journalCode=icey20
DOI
10.3109/02713683.2014.884596
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/35537
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Pathology (병리학)
공개 및 라이선스
  • 공개 구분공개
  • 엠바고Forever
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.