계명대학교 의학도서관 Repository

Lymphadenectomy increases the prognostic value of the revised 2009 FIGO staging system for endometrial cancer: A multi-center study

Metadata Downloads
Author(s)
H.S. KimH.Y. KimC.Y. ParkJ.M. LeeJ.K. LeeC.H. ChoS.M. KimJ.W. Kim
Keimyung Author(s)
Cho, Chi Heum
Department
Dept. of Obstetrics & Gynecology (산부인과학)
Journal Title
European Journal of Surgical Oncology
Issued Date
2012
Volume
38
Issue
3
Abstract
Background: We investigated whether pelvic or para-aortic lymphadenectomy increases the prognostic value of the revised 2009 FIGO
staging system in patients with endometrial cancer (EC).
Methods: We reviewed 786 patients with EC from six tertiary medical centers between July 1996 and June 2008. All patients were classified
according to the 1988 FIGO staging system: IA (n ¼ 234); IB (n ¼ 270); IC (n ¼ 109); IIA (n ¼ 35); IIB (n ¼ 29); IIIA (n ¼ 37); IIIB
(n ¼ 3); IIIC (n ¼ 69), and the revised 2009 FIGO staging system was also applied to divide them: IA (¼542); IB (¼125); II (n ¼ 29); IIIA
(n ¼ 18); IIIB (n ¼ 3); IIIC1 (n ¼ 43); IIIC2 (n ¼ 26). Prognostic values between the 1988 and the revised 2009 FIGO staging systems were
compared by multivariate Cox’s proportional hazard analysis.
Results: The 1988 FIGO stage IC, IIB, IIIA þ IIIB and IIIC, and the revised 2009 FIGO stage IB, II, IIIA þ IIIB and IIIC2 diseases were
prognostic factors for poor PFS, whereas the 1988 FIGO stage IIB and IIIC, and the revised 2009 FIGO stage II, IIIA þ IIIB and IIIC2
diseases were unfavorable prognostic factors for OS. Although these results were similar to those in 595 patients who underwent pelvic or
para-aortic lymphadenectomy, the revised 2009 FIGO stage IIIC1 disease was an additional prognostic factor for poor PFS and OS (adjusted
HRs, 4.19 and 11.25; 95% CIs, 1.39e12.60 and 2.23e36.74).
Conclusions: The revised 2009 FIGO staging system had a higher prognostic value than the 1988 FIGO staging system, and pelvic or paraaortic
lymphadenectomy increased the prognostic value of the revised 2009 FIGO staging system for EC.
2011 Elsevier Ltd. All rights reserved.
Keywords: Lymphadenectomy; The revised 2009 FIGO staging system; Endometrial cancer
Introduction
Endometrial cancer (EC) is the seventh most common
malignancy in
Keimyung Author(s)(Kor)
조치흠
Publisher
School of Medicine
Citation
H.S. Kim et al. (2012). Lymphadenectomy increases the prognostic value of the revised 2009 FIGO staging
system for endometrial cancer: A multi-center study. European Journal of Surgical Oncology, 38(3), 230–237. doi: 10.1016/j.ejso.2011.12.023
Type
Article
ISSN
0748-7983
Source
http://lps3.www.sciencedirect.com.proxy.dsmc.or.kr/science/article/pii/S0748798311007475?via%3Dihub
DOI
10.1016/j.ejso.2011.12.023
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/35662
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Obstetrics & Gynecology (산부인과학)
공개 및 라이선스
  • 공개 구분공개
  • 엠바고Forever
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.