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Antifungal and physical characteristics of modified denture base acrylic incorporated with silver nanoparticles

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Author(s)
Ki-Young NamCheong-Hee LeeChul-Jae Lee
Keimyung Author(s)
Nam, Ki Young
Department
Dept. of Dentistry (치과학)
Journal Title
Gerodontology
Issued Date
2012
Volume
29
Issue
2
Abstract
Objective: This study evaluated the antifungal and physical characteristics of denture base acrylic com-
bined with silver nanoparticles.
Materials and methods: Polymerized denture acrylic disc specimens containing 0 (control), 1.0, 5.0,
10.0, 20.0 and 30.0 wt% of silver nanoparticles were placed on separate culture plate dish and 100 ı`L
samples of yeast suspension of Candida albicans strain were inoculated on each specimens and incubated at
37C, for 24 h. The antifungal effects were evaluated as a number of viable cells in retrieved fu ngal
suspension. To characterize physical aspects, specimens were tested for elution of silver cation (Ag
+
)at24h
and 30th day, thermal analysis (TG/DTA), scanning electron microscope and energy disper sed X-ray
analysis (SEM/EDX) and color stability.
Results: Significant reduced CFU was exhibited at 20.0 and 30.0 wt% of silver nanoparticles incorporated
(p < 0.01) an d Ag
+
elution f rom specimens (maximum 0.356 ± 0.11 mg/L) contributed little to the anti -
fungal activity considering MIC of Ag
+
in this study (3.0 mg/L) . The successful synthesis of modified
denture acrylic containing silver nanoparticles was accessed by TG/DTA and EDX analysis.
Conclusion: The modified denture base acrylic combined with silver nanoparticles displa yed antifungal
properties and acted like latent antifungal material itself with low-releasing Ag
+
, however, the improve-
ment of poor color stability was still required.
Keywords: silver nanoparticles, denture base acrylic, antifungal effect.
Keimyung Author(s)(Kor)
남기영
Publisher
School of Medicine
Citation
Ki-Young Nam et al. (2012). Antifungal and physical characteristics of modified denture
base acrylic incorporated with silver nanoparticles. Gerodontology, 29(2), e413–e419. doi: 10.1111/j.1741-2358.2011.00489.x
Type
Article
ISSN
0734-0664
DOI
10.1111/j.1741-2358.2011.00489.x
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/35779
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Dentistry (치과학)
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