계명대학교 의학도서관 Repository

Role of body mass index as a risk and prognostic factor of endometrioid uterine cancer in Korean women

Metadata Downloads
Author(s)
Nan-Hee JeongJong-Min LeeJae-Kwan LeeJae Weon KimChi-Heum ChoSeok-Mo KimSang-Soo SeoChan-Yong ParkKi-Tae KimJuneyoung Lee
Keimyung Author(s)
Cho, Chi Heum
Department
Dept. of Obstetrics & Gynecology (산부인과학)
Journal Title
Gynecologic Oncology
Issued Date
2010
Volume
118
Issue
1
Abstract
Objective. We aimed to evaluate the role of body mass index (BMI) as a risk and prognostic factor of
endometrioid uterine cancer in Korean women.
Methods. The records of 937 patients with endometrioid uterine cancer treated between 2000 and 2006
in Korea were reviewed. To determine the disease risk by BMI, four age-matched controls were recruited
from healthy women (1-year age group).
Results. The obese (BMI≥25 kg/m2) and overweight (23 kg/m2≤BMI b25 kg/m2)women had an increased
risk for endometrioid uterine cancer (OR=3.161, 95% CI=2.655–3.763 and OR=1.536, 95% CI=1.260–1.873,
respectively) compared to the non-obese (BMI b23 kg/m2) women. That is, an increment of 1 kg/m2 caused an
18% increase in the endometrioid uterine cancer risk (OR=1.181, 95% CI=1.155–1.207).However, therewas no
difference in overall survival according to the BMI-based subgroups (log-rank=0.366, p=0.8328). The crude
Cox model showed that obesity was not associated with the patients' overall survival when the obese and nonobesewomenwere
compared (crude HR=0.82, 95% CI=0.40–1.66). Furthermore, therewas a significant trend
toward a better prognosis at increased increments of BMI (p for trendb0.001), but this was not found in the
multivariate analysis.
Conclusions. A high BMI was a significant risk factor for endometrioid uterine cancer in an Asian population.
However, it was not associated with overall survival, in spite of the earlier tumor stage of the obese women.
Keimyung Author(s)(Kor)
조치흠
Publisher
School of Medicine
Citation
Nan-Hee Jeong et al. (2010). Role of body mass index as a risk and prognostic factor of endometrioid uterine
cancer in Korean women. Gynecologic Oncology, 118(1), 24–28. doi: 10.1016/j.ygyno.2010.03.001
Type
Article
ISSN
0090-8258
Source
https://www.sciencedirect.com/science/article/pii/S0090825810002088?via%3Dihub
DOI
10.1016/j.ygyno.2010.03.001
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/35796
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Obstetrics & Gynecology (산부인과학)
공개 및 라이선스
  • 공개 구분공개
  • 엠바고Forever
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.