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Predictors of 12-week remission in a nationwide cohort of people with depressive disorders: the CRESCEND study

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Author(s)
Jae-Min KimSung-Wan KimRobert StewartSeon-Young KimJin-Sang YoonSung-Won JungMin-Soo LeeHyeon-Woo YimTae-Youn Jun
Keimyung Author(s)
Jung, Sung Won
Department
Dept. of Psychiatry (정신건강의학)
Journal Title
Human Psychopharmacology
Issued Date
2011
Volume
26
Issue
1
Abstract
Objective To estimate the 12-week remission rate of patients with depressive disorders and predictors of this in a naturalistic clinical
setting in South Korea.
Methods For people with DSM-IV depressive disorders about to receive treatment at 18 hospitals, data on sociodemographic and health
status were obtained. A free choice of clinical interventions was allowed and naturalistic follow-up took place at 1, 2, 4, 8, and 12 weeks later.
Remission was defined as a Hamilton Depression Rating Scale score of 7 sustained to 12 weeks or last follow-up, if earlier.
Results For 723 participants, the 12-week remission rate was 31.4%. Remission was more likely in women, and in patients without a prior
history of suicide attempt, and those with lower baseline anxiety.
Conclusions Remission associated with unrestricted clinical interventions was comparable to STAR

D estimates for citalopram alone.
Comorbid anxiety and previous suicide attempt were markers of worse outcome. Copyright # 2011 John Wiley & Sons, Ltd.
key words — depression; remission; anxiety; parasuicide; Korea
Keimyung Author(s)(Kor)
정성원
Publisher
School of Medicine
Citation
Jae-Min Kim et al. (2011). Predictors of 12-week remission in a nationwide cohort of
people with depressive disorders: the CRESCEND study. Human Psychopharmacology, 26(1), 41–50. doi: 10.1002/hup.1168
Type
Article
ISSN
0885-6222
Source
https://onlinelibrary.wiley.com/doi/abs/10.1002/hup.1168
DOI
10.1002/hup.1168
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/35844
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Psychiatry (정신건강의학)
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