계명대학교 의학도서관 Repository

Incidence and predictors of silent embolic cerebral infarction following diagnostic coronary angiography

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Author(s)
In-Cheol KimSeung-Ho HurNam-Hee ParkDong-Hwan JunYun-Kyeong ChoChang-Wook NamHyungseop KimSeong-Wook HanSae-Young ChoiYoon-Nyun KimKwon-Bae Kim
Keimyung Author(s)
Kim, In CheolHur, Seung HoCho, Yun KyeongNam, Chang WookKim, Hyung SeopHan, Seong WookKim, Yoon NyunKim, Kwon BaePark, Nam HeeChoi, Sae Young
Department
Dept. of Internal Medicine (내과학)
Dept. of Thoracic & Cardiovascular Surgery (흉부외과학)
Journal Title
International Journal of Cardiology
Issued Date
2011
Volume
148
Issue
2
Abstract
Background: Coronary angiography (CAG) is an invasive diagnostic procedure, which could lead to procedure
related complications. One of the well known post-procedural complications is cerebral embolic infarction
with or without symptoms. Silent embolic cerebral infarction (SECI) has clinical significance because it can
progress to a decline in cognitive function and increase the risk of dementia in the long term. The aim of this
study was to detect the incidence and predictors of SECI after diagnostic CAG using diffusion-weighted
magnetic resonance imaging (DW-MRI).
Methods: A total of 197 patients with coronary artery disease who underwent DW-MRI for evaluation of
intracranial vasculopathy before coronary artery bypass graft surgery were retrospectively enrolled in the
present study. DW-MRI was performed within 48 h after diagnostic CAG. SECI was diagnosed as presence of
focal bright high signal intensity in DW-MRI. Patients were divided into groups according to presence/
absence of SECI (+ SECI vs.− SECI, respectively). The clinical and angiographic characteristics were analyzed
and independent predictors were evaluated.
Results: Of the 197 patients, SECI occurred in 20 patients (10.2%) after diagnostic CAG. Age, female gender,
frequency of underlying atrial fibrillation, extent of coronary disease, and fluoroscopic time during diagnostic
CAG were not different between the + SECI and − SECI groups. Left ventricular ejection fraction was
significantly lower in the + SECI group than in the − SECI group (45.9±8.5% vs. 51.4±13.1%, p=0.014)
and performance rate of internal mammary artery (IMA) angiography was significantly higher in the + SECI
group compared with the − SECI group (85% vs. 37.2%, pb0.001). By multivariate analysis, performing IMA
angiography was the only predictor of SECI (OR=14.642; 95% CI=3.201 to 66.980, p=0.001).
Conclusions: The incidence of SECI after diagnostic CAG was not infrequent. Diagnostic CAG with IMA
angiography may increase the risk of SECI.
Keimyung Author(s)(Kor)
김인철
허승호
조윤경
남창욱
김형섭
한성욱
김윤년
김권배
박남희
최세영
Publisher
School of Medicine
Citation
In-Cheol Kim et al. (2011). Incidence and predictors of silent embolic cerebral infarction following diagnostic
coronary angiography. International Journal of Cardiology, 148(2), 179–182. doi: 10.1016/j.ijcard.2009.10.053
Type
Article
ISSN
0167-5273
Source
https://www.sciencedirect.com/science/article/pii/S0167527309015721?via%3Dihub
DOI
10.1016/j.ijcard.2009.10.053
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/35891
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. School of Medicine (의과대학) > Dept. of Thoracic & Cardiovascular Surgery (흉부외과학)
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