Implications of a bioresorbable vascular scaffold implantation
on vessel wall strain of the treated and the adjacent segments
- Author(s)
- Christos V. Bourantas; Hector M. Garcia-Garcia; Carlos A. M. Campos; Yao-Jun Zhang; Takashi Muramatsu; Marie-Angèle Morel; Shimpei Nakatani; Xingyu Gao; Yun-Kyeong Cho; Yuki Isibashi; Frank J. H. Gijsen; Yoshinobu Onuma; Patrick W. Serruys
- Keimyung Author(s)
- Cho, Yun Kyeong
- Department
- Dept. of Internal Medicine (내과학)
- Journal Title
- International Journal of Cardiovascular Imaging
- Issued Date
- 2014
- Volume
- 30
- Issue
- 3
- Abstract
- Background Metallic stents change permanently
the mechanical properties of the vessel wall. However
little is known about the implications of bioresorbable
vascular scaffolds (BVS) on the vessel wall strain. Methods
Patients (n = 53) implanted with an Absorb BVS that had
palpographic evaluation at any time point [before device
implantation, immediate after treatment, at short-term
(6–12 months) or mid-term follow-up (24–36 months)]
were included in the current analysis. The palpographic
data were used to estimate the mean of the maximum strain
values and the obtained measurements were classified
using the Rotterdam classification (ROC) score and
expressed as ROC/mm. Results Scaffold implantation led
to a significant decrease of the vessel wall strain in the
treated segment [0.35 (0.20, 0.38) vs. 0.19 (0.09, 0.29);
P = 0.005] but it did not affect the proximal and distal
edge. In patients who had serial palpographic examination
the vessel wall strain continued to decrease in the scaffolded
segment at short-term [0.20 (0.12, 0.29) vs. 0.14
(0.08, 0.20); P = 0.048] and mid-term follow-up [0.20
(0.12, 0.29) vs. 0.15 (0.10, 0.19), P = 0.024]. No changes
were noted with time in the mechanical properties of the
vessel wall at the proximal and distal edge. Conclusions
Absorb BVS implantation results in a permanent alteration
of the mechanical properties of the vessel wall in the
treated segment. Long term follow-up data are needed in
order to examine the clinical implications of these findings.
Keywords Bioresorbable vascular scaffold
Palpography Vessel wall strain
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