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Clinical manifestations of arrhythmogenic right ventricular cardiomyopathy in Korean patients

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Author(s)
Yongkeun ChoTaein ParkDonggu ShinJang Hoon LeeHyeon Min RyuGui-Lyen JangDong-Yeub LeeYongwhi ParkHyunsang LeeHyungseop KimSeung Chul ShinJung-Ho HeoHyunjae KangBong-Ryull LeeDeuk-Young NahDong Heon YangHun Sik ParkShung-Chull ChaeJae-Eun JunWee-Hyun Park
Keimyung Author(s)
Kim, Hyung Seop
Department
Dept. of Internal Medicine (내과학)
Journal Title
International Journal of Cardiology
Issued Date
2007
Volume
122
Issue
2
Abstract
Background: The clinical manifestations of the Korean patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) are not well
known.
Methods: The clinical data of Korean patients who met the Task Force Criteria for ARVC were analyzed.
Results: Thirty-seven patients (41.2±14.8 years old, 19 males) were diagnosed with ARVC. The commonest presenting symptoms were
palpitations (30%), syncope/presyncope (30%) and no symptoms (30%). Four patients had a family history of premature sudden death or
ARVC. Most patients with no symptoms were evaluated due to ECG abnormalities or asymptomatic ventricular arrhythmias. Ventricular
tachycardia, ventricular fibrillation and frequent premature ventricular contractions only were observed in 35%, 5% and 24%, respectively.
Wall motion abnormalities of the right and left ventricles were detected in 92% and 41%, respectively. Fatty or fibrofatty infiltration was
observed in 26 of the 32 (81%) patients who underwent an endomyocardial biopsy. Two patients had signs of heart failure. Two patients with
syncope/presyncope were diagnosed with vasovagal syncope and another was due to side effects from a medication. Most of the patients with
ventricular arrhythmias were treated with β-blockers and/or amiodarone. Implantable cardioverter-defibrillators (ICDs) were implanted in 3
patients. During a mean follow-up of 27.4±26.5 months no syncope or sudden death developed except for in one patient with an ICD who
suffered from recurrent shocks due to ventricular fibrillation.
Conclusions: ARVC may be an important cause of syncope, ventricular arrhythmias, and ECG and wall motion abnormalities of the
ventricles in Koreans. The Korean patients with ARVC exhibited various clinical manifestations.
© 2006 Elsevier Ireland Ltd. All rights reserved.
Keimyung Author(s)(Kor)
김형섭
Publisher
School of Medicine
Citation
Yongkeun Cho et al. (2007). Clinical manifestations of arrhythmogenic right ventricular
cardiomyopathy in Korean patients. International Journal of Cardiology, 122(2), 137–142. doi: 10.1016/j.ijcard.2006.11.070
Type
Article
ISSN
0167-5273
Source
https://www.sciencedirect.com/science/article/pii/S0167527306014689?via%3Dihub
DOI
10.1016/j.ijcard.2006.11.070
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/35968
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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