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A prospective randomized study on the use of nadroparin calcium in the prophylaxis of thromboembolism in Korean patients undergoing elective total hip replacement

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Author(s)
M. C. YooC. S. KangY. H. KimS. K. Kim
Keimyung Author(s)
Kang, Chang Soo
Department
Dept. of Orthopedic Surgery (정형외과학)
Journal Title
International Orthopaedics
Issued Date
1997
Volume
21
Issue
6
Abstract
Summary. Because of the belief that post-operative
deep vein thrombosis (DVT) is rare in Asian patients,
thromboprophylaxis is not usually prescribed
for surgical patients. This study reports an
open multi-centre controlled study of the use of a
low molecular weight heparin, nadroparin calcium
(Fraxoparine Sanofi France), as opposed to no
prophylaxis in 100 patients undergoing uncemented
total hip replacement. The patients had bilateral
venography performed preoperatively and 10 days
after operation. Eight patients (16%) developed
DVT in the control group of 50 patients and 1 (2%)
in the treatment group, also of 50 patients. Pulmonary
embolus occurred in 1 patient in the
treatment group and in 3 in the control group. Intraoperative
and postoperative blood loss did not
differ significantly between the two groups. Our
study suggests that the incidence of DVT in Asian
patients, though somewhat less than in their Western
counterparts, is still considerable. It confirms
the safety and efficacy of nadroparin calcium in
preventing post-operative DVT in patients undergoing
elective total hip replacement.
Keimyung Author(s)(Kor)
강창수
Publisher
School of Medicine
Citation
M. C. Yoo et al. (1997). A prospective randomized study on the use of nadroparin
calcium in the prophylaxis of thromboembolism in Korean patients
undergoing elective total hip replacement. International Orthopaedics, 21(6), 399–402. doi: 10.1007/s002640050194
Type
Article
ISSN
0341-2695
DOI
10.1007/s002640050194
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/36019
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학)
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