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Impact of High-Normal Blood Pressure Measured in Emergency Room on Adverse Cardiac Events in Acute Myocardial Infarction

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Author(s)
Nam Sik YoonMyung Ho JeongYoungkeun AhnJong Hyun KimShung Chull ChaeYoung Jo KimSeung Ho HurIn Whan SeongTaek Jong HongDonghoon ChoiMyeong Chan ChoChong Jin KimKi Bae SeungWook Sung ChungYang Soo JangJeong Gwan ChoSeung Jung Park
Keimyung Author(s)
Hur, Seung Ho
Department
Dept. of Internal Medicine (내과학)
Journal Title
Korean Circulation Journal
Issued Date
2012
Volume
42
Issue
5
Keyword
Blood pressurePrognosis
Abstract
Background and Objectives: Prehypertension according to JNC7 is common and is associated with increased vascular mortality. The importance of management in high-normal blood pressure (BP) is underemphasized. Subjects and Methods: We analyzed major adverse cardiac events (MACEs) in the Korea Acute Myocardial Infarction Registry in normal BP (group I) and high-normal BP (group II) patients. Results: Among 14871 patients, 159 (61±12.3 years, 122 males) satisfied the study indication. Six-month and one-year clinical follow-up rate was 88.9% and 85.8%, respectively. Group I had 78 patients (60.9±12.4 years). Group II had 81 patients (61.6±12.5 years). Demographics of patients were not different between groups. Treatment strategy was not different. Initial Thrombolysis in Myocardial Infarction flow grade 0 was less frequent in group II (n=32, 47.1%) than in group I (n=16, 21.9%) (p=0.001). Successful intervention rate was not different between group II (93.8%) and group I (97.1%) (p=0.590). Six-month MACE occurred in 3 patients in group I (4.4%) and 10 in group II (15.6%) (p=0.031). Compared with normal BP, the odds ratio for patients with high-normal BP was 1.147 (p=0.045, 95% confidence interval 1.011-1.402) for 6-month MACE.
Conclusion: Even though high-normal BP patients had a better baseline clinical status, the prognosis was poorer than patients with normal BP. Therapeutic BP target goal for the patients with acute myocardial infarction should be <140/90 mm Hg, which is recommended in JNC7.
Keimyung Author(s)(Kor)
허승호
Publisher
School of Medicine
Citation
Nam Sik Yoon et al. (2012). Impact of High-Normal Blood Pressure Measured in Emergency Room on Adverse Cardiac Events in Acute Myocardial Infarction. Korean Circulation Journal, 42(5), 304–310. doi: 10.4070/kcj.2012.42.5.304
Type
Article
ISSN
1738-5520
DOI
10.4070/kcj.2012.42.5.304
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/36054
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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