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Lesion Location: Its Impacts on the Procedural and Postprocedural Outcomes of Unprotected Left Main Coronary Stenting

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Author(s)
Woong KimYoung-Jo KimWon-Jae LeeSang-Hee LeeGeu-Ru HongJong-Seon ParkDong-Gu ShinBong-Sup ShimYoon-Kyung ChoHyung-Seop KimChang-Wook NamSeung-Ho HurYoon-Nyun KimKwon-Bae KimTae-Hyun YangDae-Kyung KimSung-Man KimDoo-Il KimDong-Soo Kim
Keimyung Author(s)
Cho, Yun KyeongKim, Hyung SeopNam, Chang WookHur, Seung HoKim, Yoon NyunKim, Kwon Bae
Department
Dept. of Internal Medicine (내과학)
Journal Title
Korean Circulation Journal
Issued Date
2007
Volume
37
Issue
9
Keyword
Coronary diseaseAngioplastyTreatment outcome
Abstract
Background and Objectives : Percutaneous coronary intervention (PCI) for unprotected left main coronary artery (LMCA) stenosis is a promising technique in the drug-eluting stent era. However, there is a lack of data as to the impact of the lesion location in the LMCA on the procedural and postprocedural outcomes. The aim of this study is to evaluate the effect of lesion location on the procedural and postprocedural outcomes. Subjects and Methods : From July 2003 to January 2006, we enrolled 82 patients (Males: n=49), who underwent PCI for unprotected LMCA stenosis at Yeungnam University Medical Center, Keimyung University Dong-san Hospital and In-je University Baik Hospital in Busan. The patients were divided into two groups according to the lesion location. Group 1 (n=38) was defined as those patients who had a significant stenosis in the ostium and/or body. Group 2 (n=44) was defined as those patients had a left main coronary lesion involving a bifurcation. All the patients had a sirolimus eluting stent (Cypher, Cordis) deployed into the LMCA stenosis. Stenting techniques such as the T, crush and kissing stent techniques for treating the LMCA were used at the discretion of the operator and according to the characteristics of the lesion location. The in-hospital outcomes were compared between the two groups and follow-up coronary angiography was performed after 6 months; the major adverse cardiac events (MACE) and restenosis were analyzed between the two groups. Results : The baseline characteristics between the two groups were not statistically different. The procedural outcomes showed that for the stenting methods, the conventional stent technique was the only one used in all cases of Group 1, but the kissing, T stenting and Crush techniques were also used in Group 2 (p=0.001). The clinical outcomes showed that that there was no statistical difference for the in-hospital MACEs between the two groups, but for the out-of hospital MACEs at 6 month, the target lesion revascularizatin rates, including PCI or bypass graft operation, in Group 1 were higher than those in Group 2 (0% vs 13.6%, respectively p=0.043). Both groups had one cardiac death each (2.3% vs 2.6% respectively) and there was 1 MACE in Group 1 and 7 MACEs in Group 2 (2.6% vs 16%, respectively, p=0.045). The angiographic outcomes at 6 month showed that all 8 significant restenosis cases were included in Group 2 (18%, 9.7% in the total population); the restenosis site was the left circumflex artery in all cases. Conclusion : PCI with using drug eluting stents in the left main lesion showed favorable short term outcomes in selected patients. The lesion location is also an important factor for the clinical and angiographical outcomes.
Keimyung Author(s)(Kor)
조윤경
김형섭
남창욱
허승호
김윤년
김권배
Publisher
School of Medicine
Citation
Woong Kim et al. (2007). Lesion Location: Its Impacts on the Procedural and Postprocedural Outcomes of Unprotected Left Main Coronary Stenting. Korean Circulation Journal, 37(9), 419–424. doi: 10.4070/kcj.2007.37.9.419
Type
Article
ISSN
1738-5520
DOI
10.4070/kcj.2007.37.9.419
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/36057
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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