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A Soft Tissue Perineurioma and a Hybrid Tumor of Perineurioma and Schwannoma

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Author(s)
Ji Young ParkNam Jo ParkSang Pyo KimKun Young KwonSang Sook Lee
Keimyung Author(s)
Kim, Sang PyoKwon, Kun YoungLee, Sang Sook
Department
Dept. of Pathology (병리학)
Journal Title
Korean Journal of Pathology
Issued Date
2012
Volume
46
Issue
1
Keyword
Soft tissuePerineuriomaNerve sheath neoplasmsHybrid tumor
Abstract
Perineuriomas are composed of differentiated perineurial cells. Perineuriomas have been recently recognized by the immunoreactivity for epithelial membrane antigen (EMA). Microscopically, perineuriomas show proliferation of spindle cells with wavy nuclei and delicate elongated bipolar cytoplasmic processes. The tumor cells are usually negative for the S-100 protein. Ultrastructurally, perineurial cells reveal slender, nontapered processes containing pinocytic vesicles and discontinuous basal lamina. Interestingly, hybrid tumors of benign peripheral nerve sheath tumor (PNST) have been recently reported by using immunohistochemical and ultrastructural investigations. Herein, we report a case of soft tissue perineurioma arising in the skin of a 56-year-old female; another case of a hybrid tumor of perineurioma and schwannoma in the posterior mediastinum occurred in a 53-year-old male, which is the first case of the hybrid PNST tumor reported in Korea.
Keimyung Author(s)(Kor)
김상표
권건영
이상숙
Publisher
School of Medicine
Citation
Ji Young Park et al. (2012). A Soft Tissue Perineurioma and a Hybrid Tumor of Perineurioma and Schwannoma. Korean Journal of Pathology, 46(1), 75–78. doi: 10.4132/KoreanJPathol.2012.46.1.75
Type
Article
ISSN
1738-1843
DOI
10.4132/KoreanJPathol.2012.46.1.75
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/36106
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Pathology (병리학)
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