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Cyst Ablation Using a Mixture of N-Butyl Cyanoacrylate and Iodized Oil in Patients with Autosomal Dominant Polycystic Kidney Disease: the Long-Term Results

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Author(s)
See Hyung KimSeung Hyup KimJeong Yeon Cho
Keimyung Author(s)
Kim, See Hyung
Department
Dept. of Radiology (영상의학)
Journal Title
Korean Journal of Radiology
Issued Date
2009
Volume
10
Issue
4
Keyword
Kidney cystAutosomal dominant polycystickidney diseaseCyst ablation
Abstract
Objective: We wanted to assess the long-term results of cyst ablation with using N-butyl cyanoacrylate (NBCA) and iodized oil in patients with autosomal dominant polycystic kidney disease (ADPKD) and symptomatic cysts. Materials and Methods: Cyst ablation using a mixture of NBCA and iodized oil was performed in 99 cysts from 21 patients who had such symptoms as abdominal distension and pain. The collapse or reaccumulation of the ablated cysts after the procedure was assessed during the follow-up period of 36 to 90 months. The treatment effects, including symptom relief, and the clinical data such as the blood pressure and serum creatinine levels were also assessed, together with the complications. Results: The procedure was technically successful in all 99 cysts from the 21 patients. Any procedure-related significant complications were not detected. Seventy-seven of 99 cysts (78%) were successfully collapsed on the follow-up CT. Twenty-two cysts showed reaccumulation during long-term follow-up period. The clinical symptoms were relieved in 17 of the 21 patients (76%). Four of 12 patients (33%) with hypertension and two of six patients (33%) with azotemia were improved. End stage renal disease (ESRD) occurred in six of the 21 patients (28%) during the follow-up period. The mean age of ESRD in our patients was 57 years. The mean time interval for the development of ESRD was 19 months. Conclusion: Ablation using a mixture of NBCA and iodized oil may be an effective, safe method for obtaining symptom relief in patients with ADPKD.
Keimyung Author(s)(Kor)
김시형
Publisher
School of Medicine
Citation
See Hyung Kim et al. (2009). Cyst Ablation Using a Mixture of N-Butyl
Cyanoacrylate and Iodized Oil in Patients with Autosomal Dominant Polycystic Kidney Disease: the Long-Term Results. Korean Journal of Radiology, 10(4), 377–383. doi: 10.3348/kjr.2009.10.4.377
Type
Article
ISSN
1229-6929
DOI
10.3348/kjr.2009.10.4.377
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/36113
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Radiology (영상의학)
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