계명대학교 의학도서관 Repository

Imported Malaria in Korea: a 13-Year Experience in a Single Center

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Author(s)
Hae Suk CheongKi-Tae KwonJi-Young RheeSeong Yeol RyuDong Sik JungSang Taek HeoSang Yop ShinDoo Ryun ChungKyong Ran PeckJae-Hoon Song
Keimyung Author(s)
Ryu, Seong Yeol
Department
Dept. of Internal Medicine (내과학)
Journal Title
Korean Journal of Parasitology
Issued Date
2009
Volume
47
Issue
3
Keyword
Plasmodiumimported malariaadverse drug eventsmefloquinequinine
Abstract
The incidence of imported malaria has been increasing in Korea. We reviewed data retrospectively to evaluate the epidemiology, clinical features, and outcomes of imported malaria from 1995 to 2007 in a university hospital. All patients diagnosed with imported malaria were included. Imported malaria was defined as a positive smear for malaria that was acquired in a foreign country. A total of 49 patients (mean age, 35.7 year; M : F = 38 : 11) were enrolled. The predominant malarial species was Plasmodium falciparum (73.5%), and the most frequent area of acquisition was Africa (55.1%), followed by Southeast Asia (22.4%) and South Asia (18.4%). Fourteen-patients (30.6%) suffered from severe malaria caused by P. falciparum and 1 patient (2.0%) died of multiorgan failure. Most of the patients were treated with mefloquine (79.2%) or quinine (10.2%); other antimalarial agents had to be given in 13.2% treated with mefloquine and 44.4% with quinine due to adverse drug events (ADEs). P. falciparum was the most common cause of imported malaria, with the majority of cases acquired from Africa, and a significant number of patients had severe malaria. Alternative antimalarial agents with lower rates of ADEs might be considered for effective treatment instead of mefloquine and quinine.
Keimyung Author(s)(Kor)
류성열
Publisher
School of Medicine
Citation
Hae Suk Cheong et al. (2009). Imported Malaria in Korea: a 13-Year Experience in a Single Center. Korean Journal of Parasitology, 47(3), 299–302. doi: 10.3347/kjp.2009.47.3.299
Type
Article
ISSN
0023-4001
DOI
10.3347/kjp.2009.47.3.299
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/36188
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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