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Clinical features and surgical outcomes of complete transposition of the great arteries

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Author(s)
Suk Jin HongHee Joung ChoiYeo Hyang KimMyung Chul HyunSang Bum LeeJoon Yong Cho
Keimyung Author(s)
Kim, Yeo Hyang
Department
Dept. of Pediatrics (소아청소년학)
Journal Title
Korean Journal of Pediatrics
Issued Date
2012
Volume
55
Issue
10
Keyword
Dextro-looped transposition of the great arteriesPostoperative complicationsReoperationMortality
Abstract
Purpose: This single-center study aimed to assess the clinical features and surgical approaches and outcomes of complete transposition of
the great arteries (TGA). Methods: TGA patients who had undergone surgical correction at the Kyungpook National University Hospital from January 2000 to December 2010, were retrospectively evaluated for patient characteristics, clinical manifestation, preoperative management,
intraoperative findings, postoperative progress, and follow-up status. Results: Twenty-eight patients (17 boys and 11 girls, mean age= 10.6±21.5 days) were included and were categorized as follows: group I, TGA with intact ventricular septum (n=13); group II, TGA with ventricular septal defect (VSD, n=12); and group III, TGA/VSD with pulmonary stenosis (n=3). Group I underwent the most intensive preoperative management (balloon atrial septostomy and prostaglandin E1 medication). Group II showed the highest incidence of heart failure (P<0.05). Usual and unusual coronary anatomy patterns were observed in 20 (71%) and 8 patients, respectively. Arterial and half-turned truncal switch operations were performed in 25 and 3 patients (Group III), respectively. Postoperative complications included cardiac arrhythmias (8 patients), central nervous system complications (3 patients), acute renal failure (1 patient), infections (3 patients), and cardiac tamponade (1 patient), and no statistically significant difference was observed between the groups. Group II showed the mildest aortic regurgitation on follow-up echocardiograms (P<0.05). One patient underwent reoperation, and 1 died. The overall mortality rate was 4%. Conclusion: Our study showed favorable results in all the groups and no significant difference in postoperative complication, reoperation, and mortality among the groups. However, our results were inadequate to evaluate the risk factors for reoperation and mortality owing to the small number of patients and short follow-up duration.
Keimyung Author(s)(Kor)
김여향
Publisher
School of Medicine
Citation
Suk Jin Hong et al. (2012). Clinical features and surgical outcomes of complete transposition of the great arteries. Korean Journal of Pediatrics, 55(10), 377–382. doi: 10.3345/kjp.2012.55.10.377
Type
Article
ISSN
1738-1061
DOI
10.3345/kjp.2012.55.10.377
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/36197
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Pediatrics (소아청소년학)
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