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전립선비대증 환자에서 전립선 내 염증과 급성 요폐의 상관관계

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Author(s)
하지용곽동윤장혁수박철희권선영김천일
Keimyung Author(s)
Ha, Ji YongChang, Hyuk SooPark, Choal HeeKim, Chun IlKwon, Sun Young
Department
Dept. of Urology (비뇨의학)
Dept. of Pathology (병리학)
Journal Title
Korean Journal of Urology
Issued Date
2008
Volume
49
Issue
12
Keyword
Urinary retentionProstatic hyperplasiaProstatitis
Abstract
Purpose: Acute or chronic prostatic inflammation exists to varying degrees in surgical specimens of prostates, extirpated for the treatment of benign prostatic hyperplasia (BPH). We investigated the relationship between acute urinary retention (AUR) and intraprostatic inflammation.
Materials and Methods: Between January 1997 and December 2006, 221 patients underwent transurethral resection of the prostate (TURP) for the treatment of BPH. The patients were divided into 2 groups based on the indication for surgery; an AUR group and a lower urinary tract symptoms (LUTS) group. The area of acute inflammation, the extent, and the aggressiveness of chronic inflammation were classified into four grades. The grades of inflammation, prostate volume, age, serum prostate-specific antigen (PSA), and prior medical treatment were compared between the two groups. All specimens were reviewed by one pathologist. Results: The AUR group consisted of 106 (47.9%) patients, and the LUTS group consisted of 115 (52.1%) patients. There were no statistical differences between the two groups with respect to the mean values of the age, prostate size, and severity of chronic inflammation. There was a significant relationship between AUR and the areas of acute inflammation, and the extent of chronic inflammation (p=0.014 and p=0.003, respectively). The aggressiveness of chronic inflammation had no relationship with AUR (p=0.062). The serum PSA level was higher in the AUR group than the LUTS group (11.5 vs. 5.3ng/ml, respectively).
Conclusions: The association for AUR with acute and chronic inflammation was stronger than that which existed with prostate size. Thus intraprostatic inflammation is an important risk factor in AUR.
Alternative Title
Relationship between Acute Urinary Retention and Intraprostatic Inflammation in Benign Prostatic Hyperplasia
Keimyung Author(s)(Kor)
하지용
장혁수
박철희
김천일
권선영
Publisher
School of Medicine
Citation
하지용 et al. (2008). 전립선비대증 환자에서 전립선 내 염증과 급성 요폐의 상관관계. Korean Journal of Urology, 49(12), 1081–1086. doi: 10.4111/kju.2008.49.12.1081
Type
Article
ISSN
0494-4747
DOI
10.4111/kju.2008.49.12.1081
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/36272
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Pathology (병리학)
1. School of Medicine (의과대학) > Dept. of Urology (비뇨의학)
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