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하부요로증상을 호소하는 전립선비대증 환자에서 Doxazosin의 장기 효과

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Author(s)
Jun ChoiJeong Oh LeeBo Hyun HanHyuk Soo Chang
Keimyung Author(s)
Chang, Hyuk Soo
Department
Dept. of Urology (비뇨의학)
Journal Title
Korean Journal of Urology
Issued Date
2008
Volume
49
Issue
11
Keyword
Benign prostatic hyperplasiaDoxazosin
Abstract
Purpose: The aim of this study was to evaluate the efficacy of doxazosin over 6 years in men with benign prostatic hyperplasia (BPH).
Materials and Methods: This retrospective study enrolled 33 patients with symptomatic BPH who were prescribed an alpha-blocker from January 1999 to December 2000. We evaluated the changes of International Prostate Symptom Score (IPSS), maximal flow rate (Qmax), quality of life (QoL) and residual urine volume (RUV) between before and after 6-year of treatment. Results: The percentages of improvement were 40.2% in total IPSS, 40.6% in obstructive symptom, 39.4% in irritative symptom, 44.7% in QoL, 124.8% in Qmax, 33.5% in RUV (p<0.05). Three patients (9.1%) experienced acute urinary retention and BPH-related surgery was performed in 6 patients (18.2%). Conclusions: Our study revealed that long-term treatment over 6 years with alpha-blocker resulted in significant improvements in the IPSS, QoL, Qmax and RUV.
Alternative Title
Long Term Effectiveness of Doxazosin in Men with Lower Urinary Tract Symptoms Suggesting of Benign Prostatic Hyperplasia
Keimyung Author(s)(Kor)
장혁수
Publisher
School of Medicine
Citation
Jun Choi et al. (2008). 하부요로증상을 호소하는 전립선비대증 환자에서 Doxazosin의 장기 효과. Korean Journal of Urology, 49(11), 1003–1006. doi: 10.4111/kju.2008.49.11.1003
Type
Article
ISSN
0494-4747
DOI
10.4111/kju.2008.49.11.1003
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/36280
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Urology (비뇨의학)
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