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조혈 성장인자의 종류와 접촉기간의 차이가 골수단핵세포의 집락형성에 미치는 효과

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Author(s)
권기영
Keimyung Author(s)
Kwon, Ki Young
Department
Dept. of Internal Medicine (내과학)
Institute for Medical Science (의과학연구소)
Journal Title
Korean Journal of Biological Response Modifiers
Issued Date
1997
Volume
7
Issue
1
Keyword
Bone MarrowMononuclear CellStem Cell FactorG-CSF
Abstract
Background: Stem cell factor and G-CSF along and in combination have been compared for their stimulatory and synergistic effects on ex vivo expansion of mononuclear cells & also compared for dose dependent effect of G-CSF, 1,000U/mL and 5,000U/mL of G-CSF werer used.

Method : Bone marrow cells were obtained from adult with normal marrow function and mononuclear cells were seperated using a Ficoll-Hypaque density gradient.
Result : CFU-GM were significantly increased even in 1 day exposure with growth factor than control group and also showed statistically significant increase in 7 day and 10 day of incubation with growth factors.
Conclusion : These results indicated that G-CSF and stem cell factor interact synergistically and their action on ex vivo expansion of mononuclear cell begin shortly after exposure.
Alternative Title
Ex Vivo Expansion of Marrow Mononuclear Cells with Growth Factors in Different Dosages & Duration of Exposure
Keimyung Author(s)(Kor)
권기영
Publisher
School of Medicine
Citation
권기영. (1997). 조혈 성장인자의 종류와 접촉기간의 차이가 골수단핵세포의 집락형성에 미치는 효과. Korean Journal of Biological Response Modifiers, 7(1), 55–65.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/36344
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
3. Research Institutues (연구소) > Institute for Medical Science (의과학연구소)
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