계명대학교 의학도서관 Repository

Skin hydration and collagen synthesis of AF-343 in HS68 cell line and NC/NGa mice by filaggrin expression and suppression of matrix metalloproteinase

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Author(s)
Hyun Kyu KimYoung-Jin ChunJae-We ChoYeon-su JeongJiwon HanMin Young KimBeom Joon KimKi Moon ParkJong Keun KimJae Hyun KimSoo-Muk Cho
Keimyung Author(s)
Cho, Jae We
Department
Dept. of Dermatology (피부과학)
Journal Title
Toxicological Research
Issued Date
2011
Volume
27
Issue
4
Keyword
Taraxacum platycarpumType I collagenMMP-1Smad2/3
Abstract
Extract of Taraxacum platycarpum (AF-343) has been reported to have several biological properties such as skin hydration and anti-inflammatory effects. Although clinical evidences of skin hydration and anti-inflammatory effect were proven in clinical trial, precise mechanism of skin hydration was not fully understood yet. In this study, we have focused skin hydration mechanism related filaggrin, collagen, and matrix metalloproteinase (MMP) in vitro and animal study. Herein, skin hydration mechanism of AF-343 is due to recovery of filaggrin in mice model and increased production of collagen with suppression of matrix MMP in vitro fibroblast cell line.
Keimyung Author(s)(Kor)
조재위
Publisher
School of Medicine
Citation
Hyun Kyu Kim et al. (2011). Skin hydration and collagen synthesis of AF-343 in HS68 cell line and NC/NGa mice by filaggrin expression and suppression of matrix metalloproteinase. Toxicological Research, 27(4), 225–229. doi: 10.5487/TR.2011.27.4.225
Type
Article
ISSN
1976-8257
DOI
10.5487/TR.2011.27.4.225
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/36357
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Dermatology (피부과학)
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