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Management and prevention of delayed gastric emptying after pancreaticoduodenectomy

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Author(s)
Yong Hoon Kim
Keimyung Author(s)
Kim, Yong Hoon
Department
Dept. of Surgery (외과학)
Journal Title
Korean Journal of Hepato-Biliary-Pancreatic Surgery
Issued Date
2012
Volume
16
Issue
1
Keyword
PancreaticoduodenectomyDelayed gastric emptyingTherapyPrevention
Abstract
Although technical advances have been made in pancreaticoduodenectomy, the incidence of delayed gastric emptying (DGE) is reported as being high. Postoperative DGE is not fatal, but often results in prolonging the length of patients’ stay in hospital, increasing their medical expenses, and further lowering their quality of life. DGE is a complex process caused by disorder and incoordination of various factors in charge of gastric mobility, such as smooth muscle cells (myogenic), enteric neuron (hormonal), and autonomic nervous system (neural). DGE often occurs after operative maneuvers that cause the loss of organs responsible for gastric motility and emptying or kinetic muscular or neuromuscular ischemia. To prevent DGE, it is most important to develop and universalize a standardized surgical technique in a way to reduce factors that are considered to cause DGE after pancreaticoduodenectomy. Moreover, if it is suspected that DGE occurred after pancreaticoduodenectomy, a differential diagnosis from diseases with similar symptoms via an accurate diagnostic approach should be implemented.


Although technical advances have been made in pancreaticoduodenectomy, the incidence of delayed gastric emptying (DGE) is reported as being high. Postoperative DGE is not fatal, but often results in prolonging the length of patients’ stay in hospital, increasing their medical expenses, and further lowering their quality of life. DGE is a complex process caused by disorder and incoordination of various factors in charge of gastric mobility, such as smooth muscle cells (myogenic), enteric neuron (hormonal), and autonomic nervous system (neural). DGE often occurs after operative maneuvers that cause the loss of organs responsible for gastric motility and emptying or kinetic muscular or neuromuscular ischemia. To prevent DGE, it is most important to develop and universalize a standardized surgical technique in a way to reduce factors that are considered to cause DGE after pancreaticoduodenectomy. Moreover, if it is suspected that DGE occurred after pancreaticoduodenectomy, a differential diagnosis from diseases with similar symptoms via an accurate diagnostic approach should be implemented.
Keimyung Author(s)(Kor)
김용훈
Publisher
School of Medicine
Citation
Yong Hoon Kim. (2012). Management and prevention of delayed gastric emptying after pancreaticoduodenectomy. Korean Journal of Hepato-Biliary-Pancreatic Surgery, 16(1), 1–6. doi: 10.14701/kjhbps.2012.16.1.1
Type
Article
ISSN
1738-6349
DOI
10.14701/kjhbps.2012.16.1.1
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/36430
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Surgery (외과학)
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