이하선 침범과 단일염색체(Monosomy) 20이 동반된 소아 급성 림프구성 백혈병 1례

Abstract

Hypodiploidy exists in 3-15% of patients with childhood acute lymphoblastic leukemia(ALL) and is associated with a poor prognosis. Monosomy 7 and monosomy 20 account for most karyotypic abnormalities in patients in whom whole chromosomes are lost and their incidences are rare. Parotid tumors in the pediatric age group are unusual and in 1996, there was a case of invasion of the parotid glands of ALL in a 6-year-old boy with swelling of both parotid glands. But invasion of acute lymphocytic leukemia to the parotid gland has not yet been reported in Korea. Here, we report a 33 month-old boy with swelling of both parotid glands who was diagnosed to have ALL with monosomy 20 & parotid gland invasion. (Korean J Pediatr 2004;47:1347-1350)