망상화한 Matriderm과 부분층 피부이식술을 이용한 화상 창상의 치료

Abstract

Purpose: Skin graft is the gold standard surgical treatment in burn wound management. But it has functional and aesthetic limitations, such as burn scar contracture, low quality of the grafted skin, unnatural looking skin, loss of skin elasticity, especially in extensive deep burn wound which has tendon or bone exposed. The authors used MatridermⓇ, a dermal analogue, with split-thickness skin graft simultaneously in burn wound and evaluate the effectiveness of MatridermⓇ for treatment of burn wounds, in comparison with the skin graft only. Methods: 40 burn patients with skin graft were included in this study. Patients were selected with their consent for inclusion in an experimental group and a control group. Patients in the experimental group received a meshed MatridermⓇ appliance and a split-thickness skin graft, while those in the control group received only a split-thickness skin graft. Time to complete epithelization, rates of skin graft taken areas, Vancouver scar scale assessment, skin elasticity was evaluated. Results: A better scores of Vancouver scar scale assessment (3 points) were observed in the experimental group with the control group (6 points) with statistical significance (P ＜0.05). A higher elasticity ratio of the affected side to the non-affected side was observed in the experimental group, compared with the control group (P＜0.05), and a similar time to complete epithelization and rates of skin graft taken areas were observed in the experimental group when compared with the control group. Conclusion: Meshed MatridermⓇ enables effective healing and improves functional and aesthetic results in split thickness skin graft treatment of burn wounds.