계명대학교 의학도서관 Repository

산후우울증 환자에서 혈중 Nitric Oxide Metabolites의 혈장 농도의 변화

Metadata Downloads
Author(s)
이분희김계현신영철김정범김용구
Keimyung Author(s)
Kim, Jung Bum
Department
Dept. of Psychiatry (정신건강의학)
Journal Title
생물정신의학
Issued Date
2006
Volume
13
Issue
1
Keyword
Postpartum depressionEPDSNitric oxideNox
Abstract
Background : Some reports have suggested that decreased nitric oxide metabolites($NO_x$) and activity of nitric oxide synthase could be related to the pathophysiology of depression. We evaluated plasma levels of $NO_x$ in pregnant women with and without postpartum depression at prenatal and postnatal period. Methods : The plasma concentrations of $NO_x$ were measured in 104 pregnant women in the third trimester and at 6 weeks postpartum and in 64 normal controls. The severity of depression and anxiety was measured with the Edinburgh Postnatal Depression Scale(EPDS), Beck Depression Inventory(BDI), and Beck Anxiety Scale(BAI). Results : Plasma $NO_x$ levels at 6 weeks postpartum were significantly lower in cases of postpartum major depression(EDPS scores${\geq}$13 points) than in cases without depression(EDPS scores${\leq}$9 points). Plasma $NO_x$ levels had significantly negative correlation with EPDS scores at 6 weeks postpartum. Conclusion : We demonstrate that decreased plasma $NO_x$ is associated with postpartum depression. Further studies are required to determine whether individual serum concentration of plasma $NO_x$ alone could predict maternal depression.
Alternative Title
Plasma Levels of Nitric Oxide Metabolites in Patients with Postpartum Depression
Keimyung Author(s)(Kor)
김정범
Publisher
School of Medicine
Citation
이분희 et al. (2006). 산후우울증 환자에서 혈중 Nitric Oxide Metabolites의 혈장 농도의 변화. 생물정신의학, 13(1), 19–25.
Type
Article
ISSN
1225-8709
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/36528
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Psychiatry (정신건강의학)
공개 및 라이선스
  • 공개 구분공개
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.