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항호중구 항체(ANCA) 양성의 소아 Wegener 육아종증 1례

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Author(s)
김원태김우정김준식강진무박관규
Keimyung Author(s)
Kim, Joon SikKang, Chin MooPark, Kwan Kyu
Department
Dept. of Pediatrics (소아청소년학)
Dept. of Pathology (병리학)
Journal Title
소아과
Issued Date
1994
Volume
37
Issue
8
Keyword
Wegener's granulomatosisAntineutrophil Cytoplasmic AntibodiesRapidly Progressive Glomerulonephritis
Abstract
Wegener's granulomatosis is a disease of unknown etiology that is characterized by the clinicopathologic complex of necrotizing granulomatous vasculitis of the upper and lower respiratory tract, glomerulonephritis, and variable degrees of small vessel vasculitis. Recently Antineutrophil Cytoplasmic Antibody (ANCA) has been reported to be a highly specific test for the diagnosis of Wegener's granulomatosis. We have experienced a patient of Wegener's granulomatosis in a 11 year old girl who was admitted with complaints of arthralgia, hematuria, convulsion and associated with otitis media and sinusitis. Serologic test of C-ANCA was poitive and histologic findings of the kidney showed crescentic glomerulonephritis with sclerosis and surrounding infiltration of multinucleated giant cells. Patient was treated with pulse methylprednisolone without improvement. The clinical course progressed rapidly and expired due to the renal failure, gastrointestinal bleeding and status epilepticus. A brief review of literatures was made.
Alternative Title
A Case of Anti-Neutrophil Cytoplasmic Antibodies (ANCA) Positive Wegener's Granulomatosis
Keimyung Author(s)(Kor)
김준식
강진무
박관규
Publisher
School of Medicine
Citation
김원태 et al. (1994). 항호중구 항체(ANCA) 양성의 소아 Wegener 육아종증 1례. 소아과, 37(8), 1175–1181.
Type
Article
ISSN
0560-3560
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/36668
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Pathology (병리학)
1. School of Medicine (의과대학) > Dept. of Pediatrics (소아청소년학)
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