소아 백혈병에서의 감염 양상

Abstract

Purpose : Infection is one of the major causes of morbidity and motality in children during chemotherapy for leukemia and the development of fever in neutropenic cancer patients frequently indicates infaction. The purpose of the present study is to evaluate infectious manifestations during the course of leukemia. Method : Seventy eight leukemic children who had one or more occasions of infection during hopitalizatio from January 1993 to December 1999 at Dong San Hospital, Keimyung University were analyzed. Infection was definded clinically as a single oral temperature of 38.5℃ or higher or as three consequent oral temperature 38℃ in a day. Result : Two-hundred and four febrile episodes were studied. The casue of infection was detected in 139 episodes while in 68 epsodes the cause was not detected. Conclusion : Infection was the most frequent cause of death in leukemic patients and fungal infections has increased recently.