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관동맥 조영술상 정상 혹은 50% 미만의 협착과 흉통을 가진 환자의 장기 추적 결과

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Author(s)
박기락배장호김기식김윤년김권배
Keimyung Author(s)
Kim, Kee SikKim, Yoon NyunKim, Kwon Bae
Department
Dept. of Internal Medicine (내과학)
Journal Title
순환기
Issued Date
2001
Volume
31
Issue
4
Keyword
AnginaPrognosisNitrates
Abstract
Background:This study was undertaken to evaluate the long-term clinical prognosis, the effects of anti-anginal
medicines and the factors of recurrence in patients with angina and insignificant coronary artery stenosis
(CAS). Methods:The study population was consisted of 372 patients with angina and normal or minimal
(less than 50% stenosed) CAS out of 2475 consecutive patients who underwent coronary angiogram over a
3.5 year period. We retrospectively reviewed the medical records of the study population. Results:Myocardial
infarction was developed in 2 cases (0.5%), recurrence of angina in 59 cases (16%), and there was no
death during mean 19-month follow-up period of the 372 patients. Patients with normal coronary artery (n=
266) were younger (mean 54 yrs vs 59 yrs, p<0.001), had a lower incidence of diabetes (5% vs 13%, p<0.01),
hypertension (19% vs 29%, p<0.05), recurrent angina (15% vs 18%, not significant), and myocardial
infarction (0.4% vs 0.9%, not significant) than patients with minimal lesion (n=106). Anti-anginal medicine
did not show benefits in relieving recurrent angina. Furthermore, in cases of patients with normal coronary
artery taking, nitrates there was a more frequent recurrence of angina (23% vs 13%, p<0.01) than seen in
similar patients not taking nitrates. There were no correlation between recurrent angina and age, sex, ischemic
changes on electrocardiogram, smoking, hypertension, diabetes, or hyperlipidemia. Conclusion:The longterm
clinical outcome in patients with insignificant CAS was good. Although there were no definitive factors
associated with the recurrence of chest pain, the administration of nitrates may cause more frequent angina in
patients with normal coronary angiography. (Korean Circulation J 2001;31(4):392-397)
Alternative Title
Long-Term Clinical Outcomes in Patients with Angina and Insignificant
Coronary Artery Stenosis
Keimyung Author(s)(Kor)
김기식
김윤년
김권배
Publisher
School of Medicine
Citation
박기락 et al. (2001). 관동맥 조영술상 정상 혹은 50% 미만의 협착과
흉통을 가진 환자의 장기 추적 결과. 순환기, 31(4), 392–397. doi: 10.4070/kcj.2001.31.4.392
Type
Article
ISSN
1225-164X
DOI
10.4070/kcj.2001.31.4.392
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/36746
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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