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KUMEL Repository 1. Journal Papers (연구논문) 1. School of Medicine (의과대학) Dept. of Internal Medicine (내과학)

제 2 형 당뇨병 동물 모델인 OLETF ( Otsuka Long - Evans Tokushima Fatty ) 쥐에서 a - lipoic acid 에 의한 혈관기능장애의 회복

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Author(s)
정윤이; 김현식; 고정민; 한정희; 박중열; 배성원; 조인호; 홍성관; 이인규; 박성욱; 박승정; 이기업
Keimyung Author(s)
Lee, In Kyu
Department
Dept. of Internal Medicine (내과학)
Journal Title
한국지질동맥경화학회
Issued Date
2001
Volume
11
Issue
2
Keyword
OLETF rat; Atherosclerosis; Endothelium-dependent vasorelaxation; a-Lipoic acid; Diabetes
Abstract
Objective : It has been suggested that increased oxidative stress contributes to atherogenesis and endothelial dysfunction.
Methods : OLETF rats at 12 weeks of age were divided into two groups, and were given diet with(n=6) or without(n=11) 5% a-lipoic acid.
Results : Endothelium-dependent and independent vasorelaxation was impaired in OLETE rats.
Conclusion : OLETE rats showed impaired responsiveness in endothelium-dependent and endothelium-independent vasorelaxation and decreased urinary NO excretion.
Alternative Title
Improvement of Vascular Dysfunction by a - Lipoic Acid in OLETF ( Otsuka Long - Evans Tokushima Fatty ) Rats
Keimyung Author(s)(Kor)
이인규
Publisher
School of Medicine
Citation
정윤이 et al. (2001). 제 2 형 당뇨병 동물 모델인 OLETF ( Otsuka Long - Evans Tokushima Fatty ) 쥐에서 a - lipoic acid 에 의한 혈관기능장애의 회복. 한국지질동맥경화학회, 11(2), 209–218.
Type
Article
ISSN
1226-4393
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/37162
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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