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췌장 베타세포 KATP channel에 대한 아연이온의 차단효과가 세포내 ATP 농도에 의존적인 원인

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Author(s)
안영호송대규
Keimyung Author(s)
Song, Dae Kyu
Department
Dept. of Physiology (생리학)
Institute for Medical Science (의과학연구소)
Journal Title
항공우주의학
Issued Date
1999
Volume
9
Issue
1
Keyword
KATP channelPancreatic beta cellZinc blockadeIntracellular ATP
Abstract
In order to clarify the cause of intracellular ATP dependency on Zn2+ blockade of KATP channels in pancreatic beta cells, we investigated the KATP channel activity during external Zn2+ application using voltage clamp technique. Cultured beta cells were used for patch-clamp experiment. When 3 mM glucose was applied in bath, KATP channel activity was increased transiently by externally applied Zn2+ in the cell-attached mode and was recoverable.
Alternative Title
Cause of Intracellular ATP Dependency on Zn²⁺ Blockade of KATP Channels in Pancreatic Beta Cells
Keimyung Author(s)(Kor)
송대규
Publisher
School of Medicine
Citation
안영호 and 송대규. (1999). 췌장 베타세포 KATP channel에 대한 아연이온의 차단효과가 세포내 ATP 농도에 의존적인 원인. 항공우주의학, 9(1), 77–82.
Type
Article
ISSN
1738-2548
Source
http://www.dbpia.co.kr/Journal/ArticleDetail/NODE01373286
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/37194
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Physiology (생리학)
3. Research Institutues (연구소) > Institute for Medical Science (의과학연구소)
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