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흰쥐에서 체중, 수분섭취량 및 혈액학적 변동에 대한장시간의 Head-down Suspension의 영향

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Author(s)
배재훈송대규김대광
Keimyung Author(s)
Bae, Jae HoonSong, Dae KyuKim, Dae Kwang
Department
Dept. of Physiology (생리학)
Dept. of Medical Genetics (의학유전학)
Brain Research Institute (뇌연구소)
Journal Title
항공우주의학
Issued Date
2002
Volume
12
Issue
2
Keyword
Head-down suspensionBody weightWater intakeHemoglobinHematocrit
Abstract
Background : This study was aimed to observe the changes in body weight, water intake and hematological data during and after long-term head-down suspension (HDS) in rats. HDS rats induced by tail suspension has evolved as a useful model for the simulation of a microgravity or zero-gravity environment.
Methods : Unanesthetized, unrestrained, male Sprague-Dawley rats, weighing 230-370 g, were subjected to either a horizontal position (control horizontal, CH rats) of a 45° head-down suspension (HDS rats) for 4 weeks. We determined the body weight and daily water intake in both CH and HDS rats.
Result : In CH rats, body weight was significantly increased (p<0.05) after 4 weeks of experiment, whereas the body weight of HDS rats was only showed a small increased but was significantly decreased (p<0.05) after 4 weeks of HDS compared with that of CH rats.
Conclusion : These results represent that the long-terms HDS could attenuate the increase in body weight of young rats and induce the decrease in hematololgical data, especially in the characteristics of red blood cell.
Alternative Title
Effects of Long-Term Head-down Suspension on Changes in Body Weight, Daily Water Intake and Hematological Data in Rats
Keimyung Author(s)(Kor)
배재훈
송대규
김대광
Publisher
School of Medicine
Citation
배재훈 et al. (2002). 흰쥐에서 체중, 수분섭취량 및 혈액학적 변동에 대한장시간의 Head-down Suspension의 영향. 항공우주의학, 12(2), 65–71.
Type
Article
ISSN
1738-2548
Source
http://www.dbpia.co.kr/Journal/ArticleDetail/NODE01369267
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/37199
Appears in Collections:
3. Research Institutues (연구소) > Brain Research Institute (뇌연구소)
1. School of Medicine (의과대학) > Dept. of Medical Genetics (의학유전학)
1. School of Medicine (의과대학) > Dept. of Physiology (생리학)
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