부정형 Kawasaki 병

Abstract

Clinical analysis was done on 13 cases of atypical Kawasaki disease who had prolonged high fever of unknown etiology associated with less than two clinical diagnostic criteria for Kawasaki disease and also had coronary abnormality on two dimensional echocardiography. Following results were obtained. 1) Among 13 cases, 9 cases were male and mean age was 28.2 months. 2) Body temperature was ranged between 38.5 — 40.6'C and the mean duration of febrile illness was 11.7 days. 3) Clinical Symptoms other than fever were bulbar conjunctival congestion in 46.2%, lips and oral cavity changes in 61.5%, cervical lymphadenopathy in 23.1%, polymorphous exanthema in 30.8% and changes of peripheral extremities in 38.5%. 4) Thrombocytes on admission were over 450,000/mm3 in 76.9% and the mean was 547,846/mm3. 5) ESR was elevated in all cases. 6) Echocardiogram revealed left main coronary artery dilatation in 84.6% of the cases. These results were almost same patterns which were observed in 64 cases of typical Kawasaki disease, seen during the same period in Dong San hospital. This analysis suggests that the diagnosis of Kawasaki disease be considered in an infants or children with a prolonged unexplained high fever and a partial criteria for Kawasaki disease and initiated prompt anti-platelet therapy to prevent or decrease the mortality and serious coronary complications.