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비알코올성 지방간질환에 대한 이해와 비약물적 중재 및 측정지표에 대한 문헌분석

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Author(s)
김나현
Keimyung Author(s)
Kim, Na Hyun
Department
Dept. of Nursing (간호학)
Research Institute for Nursing Science (간호과학연구소)
Journal Title
Journal of Korean Biological Nursing Science
Issued Date
2013
Volume
15
Issue
2
Abstract
Purpose: This study was intended to analyze the types and measurement parameters of non-pharmacological interventional studies for nonalcoholic fatty liver disease (NAFLD). Methods: NAFLD related literatures were systematically reviewed. The existing literatures were searched electronically using the data base of PubMed, a Medline data base of the National Library of Medicine with the key words of nonalcoholic fatty liver disease, NAFLD, nonalcoholic steatohepatitis, and NASH. The criteria for inclusion in this review were 1) non-pharmacological intervention, 2) human, 3) English. Finally, 20 articles were included in the review. Results: The major findings of this study were as follows: 1) the types of non-pharmacological intervention were exercise (35%), caloric restriction (30%), and lifestyle modification with combination both of exercise and caloric restriction (35%), 2) Almost all studies adopted various measurement parameters derived from pathophysiological mechanism-based biomarkers such as anthropometric indices, biochemical parameters, body fat mass, and liver biopsy results. Conclusion: Non-pharmacological interventions have been reported to be effective to improve NAFLD status, and many objective biomarkers confirmed supported these findings. Therefore, the development of nursing interventions for NAFLD subjects is needed and the consideration of using mechanism-based biomarkers is suggested to verify nursing outcomes objectively.
Key Words: Nonalcoholic fatty liver disease; Non-pharmacological intervention study
Alternative Title
The Analysis of Non-pharmacological Intervention Study for Nonalcoholic Fatty Liver Disease: Intervention Types and Measurement Parameters
Keimyung Author(s)(Kor)
김나현
Publisher
College of Nursing
Citation
김나현. (2013). 비알코올성 지방간질환에 대한 이해와 비약물적 중재 및 측정지표에 대한 문헌분석. Journal of Korean Biological Nursing Science, 15(2), 43–53. doi: 10.7586/jkbns.2013.15.2.43
Type
Article
ISSN
1229-6155
DOI
10.7586/jkbns.2013.15.2.43
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/37390
Appears in Collections:
2. College of Nursing (간호대학) > Dept. of Nursing (간호학)
3. Research Institutues (연구소) > Research Institute for Nursing Science (간호과학연구소)
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