계명대학교 의학도서관 Repository

Heart Rate Variability and Metabolic Syndrome in Hospitalized Patients with Schizophrenia

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Author(s)
Lee, KyungheePark, JeongeonChoi, JeongimPark, Chang Gi
Keimyung Author(s)
Lee, Kyung Hee
Department
Dept. of Nursing (간호학)
Journal Title
대한간호학회지
Issued Date
2011
Volume
41
Issue
6
Abstract
Purpose: Reduced heart rate variability significantly increases cardiovascular mortality. Metabolic syndrome increases the cardiac autonomic dysfunction. Recently, increasing cardiovascular mortality has been reported in patients with schizophrenia. This study was done to compare heart rate variability between adults with and without schizophrenia and to compare the relationship of heart rate variability to metabolic syndrome in hospitalized patients with schizophrenia. Methods: This was a descriptive and correlational study in which 719 adults without schizophrenia and 308 adults with schizophrenia took part between May and June 2008. We measured the following: five-minute heart rate variability; high-frequency, low-frequency, the ratio of low-frequency to high-frequency, and the Standard Deviation of all the normal RR intervals. Data was also collected on metabolic syndrome, abdominal obesity, triglycerides, HDL cholesterol, blood pressure and fasting glucose. Results: The Standard Deviation of all the normal RR intervals values of heart rate variability indices were 1.53±0.18. The low-frequency and high-frequency values of heart rate variability indices were significantly higher in hospitalized patients with schizophrenia (3.89±1.36; 3.80±1.20) than those in the healthy participants (2.20±0.46; 2.10±0.46). There were no significant differences between the schizophrenic patients with and without metabolic syndrome. Conclusion: The results of this study indicate that schizophrenia patients have significantly lower cardiac autonomic control, but they have significantly higher low-frequency and high-frequency values than those of healthy adults. Use of antipsychotic drug may affect the autonomic nervous system in schizophrenic patients. Metabolic syndrome was not associated with cardiac autonomic control in schizophrenia patients.
Key words: Metabolic syndrome X, Schizophrenia
Keimyung Author(s)(Kor)
이경희
Publisher
College of Nursing
Citation
Lee, Kyunghee et al. (2011). Heart Rate Variability and Metabolic Syndrome in Hospitalized Patients with Schizophrenia. 대한간호학회지, 41(6), 788–794. doi: 10.4040/jkan.2011.41.6.788
Type
Article
ISSN
1598-2874
DOI
10.4040/jkan.2011.41.6.788
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/37530
Appears in Collections:
2. College of Nursing (간호대학) > Dept. of Nursing (간호학)
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