Gramoxone® - HCl ( Paraquat ) 중독환자 13 예에 대한 임상적 고찰

Abstract

Clinical and autopsy studies were made or. 13 cases of Paraquat poisoning admitted to the department of Internal Medicine, Keimyung University Medical College and Hospital from August 1980 to October 1981, and the following results were obtained.

1) Among 13 cases paraquat poisoning, 11 cases were male and the rest were female. Sex ratio 5. 5 ; 1. Cause of poisoning was primarily succidal attempt(84. 6%).

2) Observing of symptoms & signs of damaged organs by paraquat poisoning during admission, ora! cavity burn in all 13 cases within 3 days, transient jaundice & elevated SGOT and SGPT in 10 cases(76.9%) within 3 days, transient renal dysfunction after 3 days and respiratory dysfunction from 3 days to 2 weeks after exposure were observed.

3) Observing of damaged organs in autopsy of one case, fibrosis and fine emphysematous change of lung, diffuse ulceration of mucosa of esophagus, centrilobular biliary stasis of liver and acute tubular necrosis of kidney were observed.

4) Mortality rate was over 76.9%, the majority of them died within 3 weeks after poisoning. The main cause of death was pulmonary dysfunction.