특수한 경우의 C형 간염 치료: 만성 콩팥병
- Author(s)
- 정우진
- Keimyung Author(s)
- Chung, Woo Jin
- Department
- Dept. of Internal Medicine (내과학)
- Journal Title
- 대한내과학회지
- Issued Date
- 2015
- Volume
- 88
- Issue
- 6
- Abstract
- Hepatitis C virus (HCV) infection is prevalent in patients with chronic kidney disease, especially those on hemodialysis. Chronic
HCV infection in patients with end-stage renal disease is associated with increased morbidity and mortality in the pre- and post-kidney
transplant periods. Increased mortality is associated with liver complications and an elevated cardiovascular risk in HCV-infected
patients on hemodialysis. Antiviral treatment may improve the prognosis of patients with HCV, and standard interferon remains
the cornerstone of treatment. Direct-acting antiviral agents (DAA) are a potential new treatment modality for chronic HCV
infection. Whatever DAA combination is administered, the use of ribavirin is still problematic in this population and this might affect
the virological outcomes of some anti-HCV therapies. (Korean J Med 2015;88:647-650)
Keywords: Hepatitis C; Renal insufficiency, Chronic; Renal dialysis
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