신아밀로이드증 1예 - 전자현미경 및 면역화학적 소견 -

Abstract

A case of a 26 year old man who was found to have renal amyloidosis is reported. The patient was admitted to the Keimyung University Medical Center in April 1990 for evaluation of edema and proteinuria of 4 months duration. Seven years earlier, at the age of 19，he was transiently treated under the clinical impression of rheumatoid arthritis at the private clinic. Renal biopsy was performed after admission. The light microscopic finding showed hyaline deposits extending from the mesangium to the capillary wall in the hematoxylin and eosin stain. Congo red stain in polarized light showed orange-green birefringence of amyloid. Using the PAP method, nodular deposits of amyloid in the mesangium and hilar arteriole are stained positively with anti-AA serum. Electron microscopic finding showed randomly arranged and nonbran-ching fibrillary rods in the mesangium and basement membrane.