Tear Film Break-Up Time(BUT)에 대한 Fluorescein 농도의 영향

Abstract

The Tear Film Break-Up Time(BUT) in the diagnosis of the dry eye syndrome was widely used, but its results were variableaccordingtothe methods of measuring BUTs. Especially, the method of Fluorescein administration and concentration had a great influence on BUT. The purpose of this study was to standardize the method used in measurement of BUT, particularly fluorescein solution concentration. We measured BUT in seven groups of different fluorescein solution concentration and "total subjects were 464 persons. The results were as follows ; 1. The mean BUT was 14.24士2.04 seconds in 0.12^ Fluorescein solution, 11.73 士2.11 seconds in 0.25% solution, 11,34±3.00 seconds in 0.5^ solution, 10.3±3.50 seconds in 1% solution, 9.59 + 2.74 seconds in 2% solution, 7.56±1.84 seconds insolution and 5.55±1.20 seconds in 8% solution. 2. The more Fluorescein concentration was, the shorter BUT became and there were statistically significant decrease in 0.25%, 0.5% and 2% Fluorescein solution.