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유방 엽상종양의 재분류 및 이에 따른 임상적 특징

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Author(s)
허윤손창용김유사김상표
Keimyung Author(s)
Kim, You SahKim, Sang Pyo
Department
Dept. of Surgery (외과학)
Dept. of Pathology (병리학)
Journal Title
대한외과학회지
Issued Date
1999
Volume
56
Issue
2
Abstract
Background: Phyllodes tumors are relatively rare fibroepithelial tumors of the breast. There are no strict criteria for the classification of benign and malignant phyllodes tumor. The recurrence rate is relatively high, and no single criterion for predicting recurrence has yet been established. In an attempt to define the clinical features and their histopathological correlations, we have reviewed a total of 38 patients with original pathological diagnoses of cystosarcoma phyllodes and phyllodes tumors.
Methods: Thirty-eight cases of phyllodes tumors were reviewed. Microscopic slides were re-examined and reclassified using newly defined histologic criteria which were modified from those of Pietruszka et al. The pathologic criteria examined were the number of mitoses, the invasiveness of the tumor border, the stromal overgrowth, and the stromal cellular pleomorphism. The clinical features evaluated included age, incidence, clinical manifestation, surgical procedure, and recurrence.
Results: The mean age was 34.9土12.4 years with the peak age between 40 and 49. The yearly incidence trend showed a slow increase. Twenty-three tumors (62%) fullfilled the criteria for benign phyllodes tumors, seven tumors (19%) were borderline, and seven tumors (19%) were malignant. The mean ages of the patients with benign, borderline, and malignant phyllodes tumors were 31.9, 39.1, and 40.9 years, respectively. The sizes of the benign phyllodes tumors were smaller than those of the borderline or the malignant tumors. Recurrence was found after initial excision in two patients with benign phyllodes tumors. However, after an initial wide excision, there was no recurrence in five patients with borderline and malignant tumors.
Alternative Title
Clinical and Histopathological Correlations of Phyllodes Tumors of the Breast
Keimyung Author(s)(Kor)
김유사
김상표
Publisher
School of Medicine
Citation
허윤 et al. (1999). 유방 엽상종양의 재분류 및 이에 따른 임상적 특징. 대한외과학회지, 56(2), 174–182.
Type
Article
ISSN
1226-0053
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38222
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Pathology (병리학)
1. School of Medicine (의과대학) > Dept. of Surgery (외과학)
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