계명대학교 의학도서관 Repository

재발성 유방암 환자의 생존율 및 예후인자

Metadata Downloads
Author(s)
강선희
Keimyung Author(s)
Kang, Sun Hee
Department
Dept. of Surgery (외과학)
Journal Title
대한외과학회지
Issued Date
2007
Volume
73
Issue
3
Abstract
Purpose: Although significant advances in survival have been achieved with administering adjuvant treatments in patients with early breast carcinoma, patients with recurrent breast carcinoma usually die of their disease. There have been only a few reports on the prognostic factors of patients with recurrent disease.
Methods: Two hundred thirty nine patients were treated by this institute from 1987 to 2002. We excluded those patients who had distant metastasis within three months of primary surgery. Recurrences were diagnosed by the physical findings, image study and/or tissue biopsy. The analyzed parameters were age, the primary tumor size, the nodal status, the TNM stage, the operation method, the estrogen receptor status, the disease free interval and the site of recurrence. The univariate survival distributions were estimated by using the method of Kaplan and Meier and they were compared by using the log rank test. The potential prognostic factors were analyzed via multivariate analysis with using Cox’s proportional hazard model.
Results: The median survival time from first relapse was 19.2 months and the 2 year survival rate from recurrence was 55.7%. Univariate analysis showed that patients with negative nodal involvement, an early disease stage, positivity for estrogen receptor, a long disease free interval and nonvisceral site recurrence had significantly longer survival than the counterpart patients. Multivariate analysis showed that these factors were all independent factors with a similar relative risk, about 2.01 to 2.54.
Conclusion: Thought the number of patients included in this study is relative small, our data clearly show that an axillary lymph node status, stage, estrogen receptor positivity, a disease free interval and the metastatic site are closely associated with survival from the first recurrence.
Alternative Title
Survival from the First Recurrence and the Prognostic Factors of Patients with Recurrent Breast Cancer
Keimyung Author(s)(Kor)
강선희
Publisher
School of Medicine
Citation
강선희. (2007). 재발성 유방암 환자의 생존율 및 예후인자. 대한외과학회지, 73(3), 210–215.
Type
Article
ISSN
1226-0053
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38229
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Surgery (외과학)
Authorize & License
  • Authorize공개
Files in This Item:

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.