폐 방사선 치료 후 발생한 우측 유방의 혈관육종

Abstract

Angiosarcoma of the breast is an uncommon, extremely hostile neoplasm of vascular origin. A 55-year-old female visited our hospital for a right breast mass, which had been initially noticed 6 months previously. She had a history of previous squamous cell lung cancer (T4, N2, M0) with radiation therapy 9 years earlier. Physical examination revealed a 10 cm sized slightly movable firm mass and edematous overlying skin with congeste superficial veins and retracted nipple. Mammography showed asymmetrically increased opacity in central right breast. Ultrasonography showed a indistinctly demarcated, heterogenous, complex less-echogenic mass in upper central right breast. Core needle biopsy suggested poorly differentiated carcinoma. Chest computed tomography and whole body bone scan showed no evidence of distant metastasis. On June 29, 2007, modified radical mastectomy was performed and revealed angiosarcoma of the right breast. Adjuvant therapy was not given.