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알코올성 케톤산증 환자의 예후 인자에 대한 연구

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Author(s)
이제원양승준진상찬주명돈최우익
Keimyung Author(s)
Jin, Sang ChanChoi, Woo Ik
Department
Dept. of Emergency Medicine (응급의학)
Journal Title
대한응급의학회지
Issued Date
2009
Volume
20
Issue
1
Abstract
Purpose: This study was undertaken to evaluate the prognostic factors for patients suffering with alcoholic ketoacidosis.
Methods: We retrospectively evaluated and categorized 55 alcoholic ketoacidosis patients into two groups: the survivors (group 1) and non-survivors (group 2). We compared the general characteristics and the laboratory results, including the arterial blood gas analysis (ABGA) and the complications of the two groups, and we assessed the severity of the between the two groups by using the Acute Physiology and Chronic Health Evaluation (APACHE) Ⅱ score and the Simplified Acute Physiology Score (SAPS).
Results: There were 50 male patients (90%) and 5 female patients (10%). On laboratory testing, the levels of arterial HCO3-, total protein, albumin and serum glucose were significantly lower in group 2 than that in group 1. The levels of total bilirubin and BUN (blood urea nitrogen), the PT (prothrombin time) and the aPTT (activated partial thromboplastin time) were significantly higher in group 2 than that in group 1. Serial ABGA follow-up showed that unimproved ABGA results meant a poor prognosis. The SAPS was significantly higher for group 2 than that for group 1 (p<0.001) but the APACHE Ⅱ was not significantly different. The incidence of hepatic encephalopathy, hepatic failure and acute respiratory distress syndrome (ARDS) were higher in group 2 than that in group 1. The total bilirubin, arterial HCO3- and albumin were found to be significant prognostic factors by logistic regression analysis.
Conclusion: The poor prognostic factors for alcoholic ketoacidosis were low levels of arterial HCO3-, impaired hepatic function, the incidence of ARDS and unimproved ABGA results.
Alternative Title
The Prognostic Factors For Alcoholic Ketoacidosis
Keimyung Author(s)(Kor)
진상찬
최우익
Publisher
School of Medicine
Citation
이제원 et al. (2009). 알코올성 케톤산증 환자의 예후 인자에 대한 연구. 대한응급의학회지, 20(1), 86–94.
Type
Article
ISSN
1226-4334
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38260
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학)
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