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두경부에 발생한 종괴의 세포유전학적 분석

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Author(s)
이성숙송달원이태휘안주선장성익
Keimyung Author(s)
Song, Dal WonChang, Sung Ik
Department
Dept. of Otorhinolaryngology (이비인후과학)
Dept. of Anatomy (해부학)
Journal Title
대한이비인후과학회지
Issued Date
1994
Volume
37
Issue
4
Abstract
Cytogenetic analysis was undertaken to study oncogenesis on patients with head and neck mass. Four cases of head and neck mass revealed different pathologic diagnosis and cytogenetic analysis respectively. Case one was metastatic cancer of unknown primaiy which revealed various chromosomal aberrations. The characteristic findings were T(1 : 9) (q31 : q34), del(11)(q14) and del(11)(q23). Case two was lymphoepithelioma. The cell line showed simple chromosomal abnormality, and del(2)(q34) and del(15)(q23) were observed.
Case three was malignant lymphoma. The chromosome number was generally tetraploid range and this finding suspect this case as advanced carcinoma. Case four was reactive hyperplasia. Reactive hyperplsia is not a real neoplasm but this case showed 50% of chromosomal aberration.
Each four case had different chromosomal abnormalities respectively, therefore investigation of chromosomal abnormality through cytogenetic analysis on each mass will be helpful to understanding oncogenesis.
Alternative Title
Cytogenetic Analysis on Four Cases with Head and Neck Mass
Keimyung Author(s)(Kor)
송달원
장성익
Publisher
School of Medicine
Citation
이성숙 et al. (1994). 두경부에 발생한 종괴의 세포유전학적 분석. 대한이비인후과학회지, 37(4), 760–767.
Type
Article
ISSN
1225-035X
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38348
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Anatomy (해부학)
1. School of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학)
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