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비용환자에서 Superoxide Free Radical 생성량과 항산화 효소들의 활성도

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Author(s)
김덕준
Keimyung Author(s)
Kim, Deok Jun
Department
Dept. of Otorhinolaryngology (이비인후과학)
Journal Title
대한이비인후과학회지
Issued Date
1995
Volume
38
Issue
12
Abstract
To investigate the protective function of antioxidant enzymes against reactive oxygen species (ROS) in nasal polyp formation I measured the activity of superoxide dismutase(SOD), catalasc (CAT), and glutathione peroxidasc(GSH-Px), one of antioxidant enzymes of human being which detoxify the toxicity of ROS, also measured the superoxide free radical(onc of ROS) production, in nasal polyp and control group. The superoxide free radical production and the activity of CAT increased significantly, that of SOD increased without significantly but the activity of GSH-Px decreased significantly. This result indicates that the decreased activity of GSH-Px causes the increase of production of superoxide free radical which may participate in nasal polyp formation. But the cause of increase and decrease of the activity of antioxidant enzymes in nasal polyp is not understood exactly. I think that further study is needed about the direct relationship between antioxidant enzymes and nasal polyp formation.
Alternative Title
Levels of Superoxide Free Radicals and Antioxidant Enzymes in Nasal Polyps
Keimyung Author(s)(Kor)
김덕준
Publisher
School of Medicine
Citation
김덕준. (1995). 비용환자에서 Superoxide Free Radical 생성량과 항산화 효소들의 활성도. 대한이비인후과학회지, 38(12), 1917–1922.
Type
Article
ISSN
1225-035X
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38351
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학)
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