계명대학교 의학도서관 Repository

신장이식에 있어서 공여자와 수혜자의 성별이 예후에 미치는 영향

Metadata Downloads
Author(s)
황경규손창용김형태조원현박철희박성배김현철
Keimyung Author(s)
Kim, Hyoung TaeCho, Won HyunPark, Choal HeePark, Sung BaeKim, Hyun Chul
Department
Dept. of Surgery (외과학)
Dept. of Urology (비뇨의학)
Dept. of Internal Medicine (내과학)
Journal Title
대한이식학회지
Issued Date
1998
Volume
12
Issue
1
Abstract
The role of the donor and recipient gender have been a controversial point in the outcome of renal transplantation and the pathophysiologic mechanisms are not understood clearly. In order to evaluate the effect of gender on the renal graft survival, we reviewed our 400 consecutive living donor renal transplantation.
The patients were divided into four groups, Group 1; male donor and male recipient(n=152), Group 2; female donor and male recipient(n=61), Group 3; male donor and female recipient(n=135), and Group 4; female donor and female recipient(n=52). To estimate the transplant outcome between the groups, we analyzed patient and graft survival, acute tubular necrosis, BUN, creatinine and rejection episode for maximum 5 years after transplantation.
The level of BUN(34.7 26.4, 19.8 6.4, 30.5 14.6, 23.1 10.5 in group 1,2,3,4 respectively) and serum creatinine(2.62 2.3, 1.48 1.1, 2.24 1.2, 1.65 0.9 in group 1,2,3,4 respectively) were higher in male recipient groups regardless of donor gender. However, donor and recipient gender had no influence on post-graft blood pressure and acute tubular necrosis(p>0.05). Acute rejection episode was predominent at female donor graft than male donor graft(36.4% vs 30.1%). The 5 year graft survival in group 1,2,3,4 were 67.8, 67.2, 60.1, 72.7% and patient survival were 76.9, 75.6, 72.6, 80.5% in their orders. These results suggest that donor and recipient gender might play a role in the outcome of renal transplantation. The mechanism of these results must be analyzed by further evaluation using larger patient group.
Alternative Title
The Effect of Donor and Recipient Gender on Renal Allograft Survival
Keimyung Author(s)(Kor)
김형태
조원현
박철희
박성배
김현철
Publisher
School of Medicine
Citation
황경규 et al. (1998). 신장이식에 있어서 공여자와 수혜자의 성별이 예후에 미치는 영향. 대한이식학회지, 12(1), 1–7.
Type
Article
ISSN
1598-1711
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38426
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. School of Medicine (의과대학) > Dept. of Surgery (외과학)
1. School of Medicine (의과대학) > Dept. of Urology (비뇨의학)
공개 및 라이선스
  • 공개 구분공개
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.