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CEA Expressions in Colorectal Tumor

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Affiliated Author(s)
배옥석박성대
Alternative Author(s)
Bae, Ok SukPark, Sung Dae
Journal Title
대한대장항문학회지
ISSN
1229-8670
Issued Date
2004
Abstract
PURPOSE: The purpose of this research is to investigate the clinical usefulness of carcinoembryonic antigen (CEA) expression in colorectal cancer tissue. 0aMETHODS: We performed immunohistochemical staining of CEA on 64 surgically resected colorectal cancer tissues obtained during the period from May 2000 to May 2001. CEA expression was detected by immunohistochemistry using a CEA monoclonal antibody. The degrees of CEA expression in the tumor cell cytoplasm and the luminal secretion of the tumor gland were grouped into positive (strongly positive) and negative groups (weakly positive) by using the Sinicrobe method and were compared with clinicopathological variables.0aRESULTS: The expression rates were positive in 38 cases (59.4%) and negative in 26 cases (40.6%). The preoperative CEA level showed a higher trend in the positive group (8.23o groups and the clinicopathologic factors were not statistically significant. We observed CEA expression in the luminal secretion of the tumor gland in 41 cases. The expression rates in the luminal secretion were positive in 21 cases (51.2%) and negative in 20 cases (48.8%). No significant clinical difference were noted between the two groups. 0aCONCLUSIONS: The results suggest that CEA expression may not play a role as a prognostic factor for colorectal cancer.
Alternative Title
대장암에서 CEA의 발현
Department
Dept. of Surgery (외과학)
Publisher
School of Medicine
Citation
배옥석 et al. (2004). CEA Expressions in Colorectal Tumor. 대한대장항문학회지, 20(1), 39–45.
Type
Article
ISSN
1229-8670
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38467
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Surgery (외과학)
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