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한국인 강직성 척추염 환자의 수면의 질과 질병 활성도의 관계

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Author(s)
정혜진이태한이지민최고손창남김지민조용원김상현
Keimyung Author(s)
Son, Chang NamKim, Ji MinKim, Sang HyonCho, Yong Won
Department
Dept. of Internal Medicine (내과학)
Dept. of Neurology (신경과학)
Journal Title
Journal of Rheumatic Diseases
Issued Date
2014
Volume
21
Issue
5
Abstract
Objective. To evaluate the prevalence of sleep disturbance in Korean patients with ankylosing spondylitis (AS), and its association with disease activity and depression. Methods. Forty patients with AS and eighty healthy controls were included in this study. Sleep quality was assessed using the Korean version of Pittsburgh sleep quality index (PSQI). Depression was assessed by the Korean version of Beck depression inventory second edition (BDI-2). Ankylosing spondylitis disease activity score-C-reactive protein (ASDAS-CRP) was used to evaluate disease activity. Patients were dichotomized into a good sleeper group (PSQI≤5) and a poor sleeper group (PSQI>5). Results. The mean total PSQI score of patients with AS was 7.23±3.84. It was higher than that of the control subjects. AS patients had higher scores in all of the PSQI components, except for the use of sleep medication. Sixty percent of the AS patients were classified as poor sleepers. The mean BASDAI, ASDAS-CRP, and BDI-2 scores of the poor sleeper group were higher than that of the good sleeper group. Significantly, higher disease activity according to ASDAS-CRP was associated with poor sleep quality and depression. Multiple regression analysis revealed that the duration of morning stiffness and depression were independent risk factors that influenced poor sleep quality. Conclusion. Sleep disturbances are prevalent amongst Korean patients with AS. Lower quality of sleep is significantly associated with higher disease activity and depression. Therefore, optimal management to improve sleep quality in patients with AS is important.
Alternative Title
Relation with Sleep Disturbance and Disease Activity in Korean Patients with Ankylosing Spondylitis
Keimyung Author(s)(Kor)
손창남
김지민
김상현
조용원
Publisher
School of Medicine
Citation
정혜진 et al. (2014). 한국인 강직성 척추염 환자의 수면의 질과 질병 활성도의 관계. Journal of Rheumatic Diseases, 21(5), 241–247. doi: 10.4078/jrd.2014.21.5.241
Type
Article
ISSN
2093-940X
DOI
10.4078/jrd.2014.21.5.241
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38505
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
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