계명대학교 의학도서관 Repository

Propofol을 이용한 복강경하 담낭 절제술 마취 시 remifentanil과 fentanyl의 사용이 술 후 오심 및 구토에 미치는 영향

Metadata Downloads
Author(s)
이용철김성현김진모
Keimyung Author(s)
Lee, Yong CheolKim, Jin Mo
Department
Dept. of Anesthesiology & Pain Medicine (마취통증의학)
Journal Title
Korean Journal of Anesthesiology
Issued Date
2006
Volume
51
Issue
4
Abstract
Background: Opioids can produce postoperative nausea and vomiting (PONV). Remifentanil is a nonaccumulative ultra short-acting opioid because of its rapid systemic elimination. This rapid systemic elimination could contribute to a faster weaning from the opioid side-effects like PONV. This study compared remifentanil and fentanyl with regards to the frequency of PONV in laparoscopic cholecystectomy with using propofol.
Methods: Sixty ASA physical status I or II patients who were scheduled for laparoscopic cholecystectomy were randomly assigned to either the remifentanil group (n 30) or the fentanyl group (n 30). Anesthesia was induced with propofol, rocuronium and remifentanil (n 30, 1μg/kg) or fentanyl (n 30, 2μg/kg). After tracheal intubation, anesthesia was maintained with propofol, oxygen/air and infusion of opioid (only for remifentanil group 0.2-0.5μg/kg/min). Postoperatively (1 hr, 12 hr, and 24 hr), we recorded the visual analogue scale (VAS), the rescue meperidine consumption, the number of patients with episodes of PONV and the number of ondansetron injection.
Results: The number of PONV episodes were significantly higher in the fentanyl group at the 1-12 hr postoperative period (p < 0.05; n 8 vs. n 1, fentanyl and remifentanil, respectively). However, the incidence of PONV at 0-1 hr and 12-24 hr and the total incidence of PONV were not different between the two groups.
Conclusions: The use of ultra-short acting remifentanil instead of fentanyl can reduce PONV at 1-12 postoperative hours in the laparoscopic cholecystectomy patients. (Korean J Anesthesiol 2006 51; 400~4)
Alternative Title
Effects of Remifentanil and Fentanyl on Postoperative Nausea and Vomiting in Laparoscopic Cholecystectomy with using Propofol
Keimyung Author(s)(Kor)
이용철
김진모
Publisher
School of Medicine
Citation
이용철 et al. (2006). Propofol을 이용한 복강경하 담낭 절제술 마취 시 remifentanil과 fentanyl의 사용이 술 후 오심 및 구토에 미치는 영향. Korean Journal of Anesthesiology, 51(4), 400–404. doi: 10.4097/kjae.2006.51.4.400
Type
Article
ISSN
2005-6419
DOI
10.4097/kjae.2006.51.4.400
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38522
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Anesthesiology & Pain Medicine (마취통증의학)
공개 및 라이선스
  • 공개 구분공개
파일 목록

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.