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하부요로증상을 가진 여성 환자에서 Tamsulosin 0.2 mg 단독요법의 유효성

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Author(s)
장혁수박철희권태균김덕윤오태희정재일정세일
Keimyung Author(s)
Chang, Hyuk SooPark, Choal Hee
Department
Dept. of Urology (비뇨의학)
Journal Title
대한배뇨장애요실금학회지
Issued Date
2006
Volume
10
Issue
2
Abstract
Purpose: The study of lower urinary tact symptoms(LUTS) in women is rare except urinary incontinence, and there were even no diagnostic or therapeutic guidelines for female bladder outlet obstruction. The objective of this study was to determine the efficacy of tamsulosin 0.2 mg/day single therapy for the female patients with LUTS. Materials and Methods: A total 71 patients were evaluable. Tamsulosin 0.2 mg/day was administered orally in a nonblind design for 8 weeks. The efficacy parameters were International Prostate Symptom Score(IPSS), quality of life(QOL) score, frequency in daytime and night, maximal flow rate(Qmax), post-void residual urine volume(PVR), and changes in blood pressure and pulse rates. Changes in parameters between baseline and 8 weeks were assessed using Student's paired t-test. Results: Statistically significant changes in the total, obstructive and irritative IPSS, QOL score, daytime and night time frequency, Qmax and PVR were observed at week 8. Adverse events included dizziness in 2 patients and increased nocturia in 1 patient. There were no withdrawals resulting from adverse events. There were significant differences in systolic blood pressure, but did not cause significant hypotension events. Conclusion: Treatment with tamsulosin 0.2 mg/day in female patients with LUTS was effective and well tolerated in improving LUTS and QOL.
Keywords: Alpha-blockers; Bladder neck obstruction; Female
Alternative Title
Efficacy of Tamsulosin 0.2 mg/day in Female Patients with Lower Urinary Tract Symptoms.
Keimyung Author(s)(Kor)
장혁수
박철희
Publisher
School of Medicine
Citation
장혁수 et al. (2006). 하부요로증상을 가진 여성 환자에서 Tamsulosin 0.2 mg 단독요법의 유효성. 대한배뇨장애요실금학회지, 10(2), 140–146. doi: 10.5213/jkcs.2006.10.2.140
Type
Article
ISSN
1598-186X
DOI
10.5213/jkcs.2006.10.2.140
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38597
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Urology (비뇨의학)
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