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난소암종에서 종양 신생혈관형성과 병기와의 관계

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Author(s)
장은숙주현창이태성
Keimyung Author(s)
Chang, Eun SookLee, Tae Sung
Department
Dept. of Pathology (병리학)
Dept. of Obstetrics & Gynecology (산부인과학)
Journal Title
대한병리학회지
Issued Date
1999
Volume
33
Issue
8
Abstract
Tumor angiogenesis has been found to have prognostic significance in many tumor types for predicting an increased risk of metastasis. We assessed tumor vascularity in 28 cases of borderline malignancy and 71 cases of carcinoma of the ovary which had been resected and diagnosed, using the highly specific endothelial cell marker CD34. The numbers of microvessels were counted in 200 magnification in three highly vascularised areas. The numbers of microvessels in carcinomas were higher than that in the borderline malignancy of serous and mucinous tumors. The number of microvessels of mucinous carcinomas was significantly higher than that of serous carcinomas. There were neither significant differences in the number of microvessels according to histological tumor types (p=0.075) nor significant differences in the number of microvessels according to FIGO stages (p=0.072). But in serous carcinomas, the number of microvessels was higher in the FIGO III-IV stage than in the FIGO I-II stage (p=0.017). This study showed higher neovascularization in malignant tumor than borderline malignancy, and in the advanced stage (FIGO III-IV) than less advanced stage (FIGO I-II) of serous carcinomas.
Key Words: Angiogenesis; Ovarian carcinoma; Microvessel; FIGO stage
Alternative Title
Tumor Angiogenesis and Stage in Ovarian Carcinoma.
Keimyung Author(s)(Kor)
장은숙
이태성
Publisher
School of Medicine
Citation
장은숙 et al. (1999). 난소암종에서 종양 신생혈관형성과 병기와의 관계. 대한병리학회지, 33(8), 596–602.
Type
Article
ISSN
0379-1149
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/38605
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Obstetrics & Gynecology (산부인과학)
1. School of Medicine (의과대학) > Dept. of Pathology (병리학)
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